Results 161 to 170 of about 12,646 (242)

POD24 is a novel determinant of prognosis in patients with Waldenström macroglobulinemia. [PDF]

Blood Adv
Zanwar S, Abeykoon J, D'Sa S, Roos-Weil D, Larson DR, Colby CL, Durot E, Kastritis E, Uppal E, Tomkins O, Morel P, Mondello P, Montes L, Paludo J, Ailawadhi S, Sarosiek S, Ogunbiyi O, Cornillet-Lefebvre P, Rajkumar SV, Quinquenel A, Dispenzieri A, Fonseca R, Gertz MA, Kumar S, Dimopoulos MA, Ansell SM, Treon S, Castillo JJ, Kapoor P.   +28 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Author Correction: TMEM175, SCARB2 and CTSB associations with Parkinson's disease risk across populations. [PDF]

NPJ Parkinsons Dis
Sun W, Schulte C, Gasser T, Tan M, Global Parkinson’s Genetic Program (GP2).   +4 more
europepmc   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

If you give a mouse a poopsicle: a novel fecal microbiota transplant method for exploring the role of the gut microbiome in stress-related outcomes in mice. [PDF]

Front Immunol
Tschang MA, Deo-Campo Vuong R, Eilers B, Chac D, Waalkes A, Penewit K, Easton A, Schuessler B, Daniels R, Weil AA, Salipante SJ, Gibbons SM, Schindler AG.   +12 more
europepmc   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Semi-annual and annual mass drug administration of diethylcarbamazine and albendazole are equally effective regimens for eliminating lymphatic filariasis in Papua New Guinea. [PDF]

PLoS Negl Trop Dis
Payne MC, Sanuku N, Mancuso BE, Cheng YC, Weil GJ, Fischer PU, Laman M, Robinson LJ, Tisch DJ, King CL.   +9 more
europepmc   +1 more source

Weil's Disease.

Skin research, 1994
Ohashi, Akiko, Shimizu, Ryosuke, Fukui, Toshihiko   +2 more
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Parental intent to vaccinate children with the updated 2023-2024 COVID-19 vaccine. [PDF]

Vaccine
Groom HC, Kuntz JL, Varga AM, Smith N, Coto E, Cox SN, Babu TM, Briggs-Hagen M, Frivold C, Saydah S, Mularski RA, Boisvert C, Drummond M, Feldstein LR, Fortmann SP, MacMillan MP, McDonald D, Hollcroft M, Midgley CM, Plumb ID, Reich S, Schmidt MA, Yetz N, Grioni H, McCaffrey KM, Hatchie TL, Lo N, Lockwood C, Starita L, Englund JA, Weil AA, Carone M, Chu HY, Naleway AL.   +33 more
europepmc   +1 more source