Results 91 to 100 of about 1,167,178 (384)

The significance of shooting angle in seal shooting

open access: yesAnimal Welfare
The present study aimed to investigate the relationship between shooting angle to the head and animal welfare outcomes in the hunt of young harp seals (Pagophilus groenlandicus).
Kathrine A Ryeng, Stig E Larsen
doaj   +1 more source

Social Welfare in One-sided Matching Markets without Money [PDF]

open access: yesarXiv, 2011
We study social welfare in one-sided matching markets where the goal is to efficiently allocate n items to n agents that each have a complete, private preference list and a unit demand over the items. Our focus is on allocation mechanisms that do not involve any monetary payments.
arxiv  

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Use of an expert elicitation methodology to compare welfare impacts of two approaches for blood sampling European badgers (Meles meles) in the field

open access: yesAnimal Welfare
In the UK and Republic of Ireland, the European badger (Meles meles) is considered the most significant wildlife reservoir of the bacterium Mycobacterium bovis, the cause of bovine tuberculosis (bTB).
Adrian Colloff   +8 more
doaj   +1 more source

Welfare and Rationality Guarantees for the Simultaneous Multiple-Round Ascending Auction [PDF]

open access: yesarXiv, 2015
The simultaneous multiple-round auction (SMRA) and the combinatorial clock auction (CCA) are the two primary mechanisms used to sell bandwidth. Under truthful bidding, the SMRA is known to output a Walrasian equilibrium that maximizes social welfare provided the bidder valuation functions satisfy the gross substitutes property.
arxiv  

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

open access: yesMolecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock   +10 more
wiley   +1 more source

Development of a novel primate welfare assessment tool for research macaques

open access: yesAnimal Welfare
Primates are important species for biomedical research and ensuring their good welfare is critical for research translatability and ethical responsibility.
Emilie A Paterson   +4 more
doaj   +1 more source

Paretian social welfare relations and Baire property [PDF]

open access: yesarXiv, 2020
We study the topological and set-theoretical nature of Paretian social welfare relations in a setting with infinite time horizon. Specifically, we answer questions posed in \citet{mathias2020} about the interplay between total welfare relations satisfying Pareto and anonymity principles with subsets of real numbers not satisfying the Baire property.
arxiv  

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