Results 141 to 150 of about 3,512,211 (387)
, 2007 [Excerpt] This paper explores welfare to work policy in the UK and sets out ways in which the delivery of that policy could become more efficient and effective by making small but significant changes to the approach.
Scott-Parker, Susan
core +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Aboriginal Child Welfare [PDF]
, 2003 As the relationships between Canada’s Aboriginal peoples and the state undergo changes, the issue of Child Welfare is in the foreground; for it is around the well being, education and care of Aboriginal children that much of the painful historical ...
Blackstock, Cindy +3 more
core +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
The pedagogical implications of the commercialization of children's playgrounds in urban environments [PDF]
Nastava i Vaspitanje, 2019 This paper starts from the premise that play spaces (playgrounds and playrooms) specially designed for children are shaped by social and cultural factors, reflecting society's attitudes to childhood and a particular perception of the child, and that ...
Malović Marija
doaj
Contribution of Industrial Combinations to National Welfare [PDF]
, 1912 Magnus W. Alexander
openalex +1 more source
Using Intermediary Structures to Support Families: An International Comparison of Practice in Child Protection [PDF]
, 2001 Responses to child maltreatment can be conceptualized as a continuum, ranging from a welfare-oriented approach on one end, to a legalistic emphasis at the other end.
Freymond, Nancy Colleen
core +1 more source
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Infant Welfare: Methods of Organization and Administration [PDF]
, 1912 C. R. Henderson
openalex +1 more source