Results 161 to 170 of about 1,167,178 (384)

The roles and applications of extracellular vesicles in cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

Effect of different noise reduction techniques and template matching parameters on markerless tumor tracking using dual‐energy imaging

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To evaluate the impact of various noise reduction algorithms and template matching parameters on the accuracy of markerless tumor tracking (MTT) using dual‐energy (DE) imaging. Methods A Varian TrueBeam linear accelerator was used to acquire a series of alternating 60 and 120 kVp images (over a 180° arc) using fast kV switching, on ...
Mandeep Kaur   +9 more
wiley   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Evaluation of an EPID in vivo monitoring system using local and external independent audit measurements

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose The aim of this work was to evaluate the SunCHECK PerFRACTION, the software for in vivo monitoring using EPID images. Materials/Methods First, the PerFRACTION ability to detect errors was investigated simulating two situations: (1) variation of LINAC output and (2) variation of the phantom thickness.
Samuel Ramalho Avelino   +3 more
wiley   +1 more source

Why are some people in the UK reluctant to seek support for their pets?

open access: yesAnimal Welfare
Drawing upon data from a study examining experiences of accessing support for pets from the UK animal welfare charity Blue Cross, this paper illuminates reasons why people might not seek support when they need it. This applies to those who are struggling
Janine C Muldoon, Joanne M Williams
doaj   +1 more source

Welfare State

open access: yes, 2020
The first part of this chapter describes the main features of the Spanish Welfare State, trying to place it in a comparative perspective. The second part identifies the socioeconomic and political factors which explain its evolution since the beginning of the new century to the current situation, focusing on the attempts at recalibration of the system ...
openaire   +2 more sources

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