Results 181 to 190 of about 3,527,904 (336)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Rehabilitation outcomes following tail-fluke amputation in an Indo-Pacific bottlenose dolphin: A welfare-centered approach. [PDF]

PLoS One
Higa S, Takahashi S, Nakashima E, Kurosu Y, Ikeshima H, Yagi R, Adachi N, Ueda K, Umeyama H, Yamamoto H, Nakakita Y, Tochigi K, Kagawa T, Oka SI.   +13 more
europepmc   +1 more source

The Paradox of Redistribution and Strategies of Equality: Welfare State Institutions, Inequality and Poverty in the Western Countries

, 1998
W. Korpi, Joakim Palme
semanticscholar   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Regional brain serotonergic activity as an indicator of chronic stress and compromised welfare in fish. [PDF]

Front Endocrinol (Lausanne)
Sørensen C, Vas J, Folkedal O, Bui S, Remen M, Gunnes M, Calabrese S, Wedaa LOM, Green EAL, Øverli Ø, Höglund E.   +10 more
europepmc   +1 more source

Concept Note for the Support to Implement a National Action Plan for Healthcare Waste Management in Tanzania.2009 – 2015 [PDF]

, 2006
Ministry of Health and Social Welfare, (MoHSW)
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Societal and personal financial burden of severe asthma and impact of biologic therapy: a 19-year nationwide cost analysis. [PDF]

BMJ Open Respir Res
Håkansson KEJ, Ibsen R, Krogh NS, Søndergaard MB, Hansen S, Bjerrum AS, von Bülow A, Hilberg O, Løkke A, Bonnesen B, Kappel ME, Johansson SL, Dongo L, Borup MB, Vijdea R, Rasmussen LM, Schmid JM, Ulrik CS, Porsbjerg C.   +18 more
europepmc   +1 more source

The National Family Planning Costed Implementation Program\ud 2010 - 2015 [PDF]

, 2010
Ministry of Health and Social Welfare, (MoHSW)
core  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source