Results 201 to 210 of about 3,554,852 (355)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Association of community welfare resources and outpatient occupational therapy with psychiatric length of stay: A nationwide analysis in Japan. [PDF]

PCN Rep
Orui J, Shiraiwa K, Nishida S, Inoue T, Yamada K, Naito Y, Ishii R.   +6 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Balancing Effectiveness and Ethics: Global Systematic Review of <i>Sus scrofa</i> Population Control Methods. [PDF]

Animals (Basel)
Cukor J, Pařízková M, Linda R, Vacek Z, Skoták V.   +4 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Editorial: The future of farm animal welfare science: selected papers from the 9th International Conference on the Welfare Assessment of Animals at Farm Level (WAFL). [PDF]

Front Vet Sci
Widowski T, Chou JY, Hötzel MJ, Olmos Antillón G.   +3 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Regional brain serotonergic activity as an indicator of chronic stress and compromised welfare in fish. [PDF]

Front Endocrinol (Lausanne)
Sørensen C, Vas J, Folkedal O, Bui S, Remen M, Gunnes M, Calabrese S, Wedaa LOM, Green EAL, Øverli Ø, Höglund E.   +10 more
europepmc   +1 more source

Rapid Assessment of Ongoing Enrollment Trends of Students in Health Training Institutions in Mainland Tanzania [PDF]

, 2008
Ministry of Health and Social Welfare, (MoHSW)
core