Results 71 to 80 of about 1,167,178 (384)
Submodular Welfare Maximization [PDF]
arXiv, 2013 An overview of different variants of the submodular welfare maximization problem in combinatorial auctions. In particular, I studied the existing algorithmic and game theoretic results for submodular welfare maximization problem and its applications in other areas such as social networks.
arxiv
Welfarism and extra-welfarism: a critical overview [PDF]
Cadernos de Saúde Pública, 2017 Abstract: Rules and principles for guiding decision-making in the health care sector have been debated for decades. Here, we present a critical appraisal of the two most important paradigms in this respect: welfarism and extra-welfarism. While the former deals with the maximization of the overall sum of individual utilities as its primary outcome, the ...
openaire +8 more sources
Molecular Oncology, EarlyView.Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam +2 more
wiley +1 more source
Kicking You When You're Already Down: The Multipronged Impact of Austerity on Crime [PDF]
arXiv, 2020 The UK Welfare Reform Act 2012 imposed a series of deep welfare cuts, which disproportionately affected ex-ante poorer areas. In this paper, we provide the first evidence of the impact of these austerity measures on two different but complementary elements of crime -- the crime rate and the less-studied concentration of crime -- over the period 2011 ...
arxiv
Molecular Oncology, EarlyView.This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang +10 more
wiley +1 more source
Why We Need A New Welfare State
, 2002 Contributors to this volume - Frank Vandenbrucke (Belgian Minister for Social Affairs) Gosta Esping Andersen, Professor of Sociology at Universidad Pompeu Fabra, Barcelona, Spain Duncan Gallie, Nuffield Collage, University of Oxford Anton Hemerijck ...
G. Esping-Andersen
semanticscholar +1 more source
Molecular Oncology, EarlyView.Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang +10 more
wiley +1 more source
Maximization of Relative Social Welfare on Truthful Cardinal Voting Schemes [PDF]
arXiv, 2019 Consider the the problem of maximizing the relative social welfare of truthful single-winner voting schemes with cardinal preferences compared to the classical range voting scheme. The range voting scheme is a simple and straightforward mechanism which deterministically maximizes the social welfare.
arxiv