Results 71 to 80 of about 3,447,755 (405)
Animals, 2017 Simple Summary The Five Domains Model is a focusing device to facilitate systematic, structured, comprehensive and coherent assessment of animal welfare; it is not a definition of animal welfare, nor is it intended to be an accurate representation of ...
D. Mellor
semanticscholar +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Guidelines for the welfare and use of animals in cancer research
British Journal of Cancer, 2010 Animal experiments remain essential to understand the fundamental mechanisms underpinning malignancy and to discover improved methods to prevent, diagnose and treat cancer.
P. Workman +19 more
semanticscholar +1 more source
Lottery pricing equilibria [PDF]
, 2016 We extend the notion of Combinatorial Walrasian Equilibrium, as defined by Feldman et al. [2013], to settings with budgets. When agents have budgets, the maximum social welfare as traditionally defined is not a suitable benchmark since it is overly ...
Dughmi, Shaddin +4 more
core +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Towards Farm Animal Welfare and Sustainability
Animals, 2018 Simple Summary The protection and enhancement of farm animal welfare has become an increasingly important component of livestock systems and animal-based food supply chains in many of the more economically developed countries around the world.
H. Buller +3 more
semanticscholar +1 more source
Child Welfare: An Overview of Federal Programs and Their Current Funding [PDF]
, 2014 Child welfare services are intended to prevent the abuse or neglect of children; ensure that children have safe, permanent homes; and promote the well-being of children and their families. As the U.S.
Stoltzfus, Emilie
core +5 more sources
FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source
Welfarism and extra-welfarism: a critical overview [PDF]
Cadernos de Saúde Pública, 2017 Abstract: Rules and principles for guiding decision-making in the health care sector have been debated for decades. Here, we present a critical appraisal of the two most important paradigms in this respect: welfarism and extra-welfarism. While the former deals with the maximization of the overall sum of individual utilities as its primary outcome, the ...
openaire +8 more sources
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source