Results 31 to 40 of about 275,752 (292)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Neighbourhood Satisfaction Among Municipal Tenants in the Helsinki Metropolitan Area
Tidsskrift for boligforskningThis article analyses municipal tenants’ neighbourhood satisfaction (NS) in the Helsinki metropolitan area. If social mixing has managed to equalise differences related to the residential environment across different social groups, perceived ...
Katriina Rosengren, Timo M. Kauppinen
doaj +1 more source
Frontiers in Veterinary Science, 2021 Animal welfare is one of the most challenging issues in modern farm animal husbandry. Animal welfare indicators can be used to monitor welfare on farms or at slaughterhouses, with footpad dermatitis (FPD) being one of the most important indicators used ...
Jenny Stracke +5 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Social Work and Society, 2019 The Welfare states in Europe are changing. Traditional strategies of welfare which are based on income-replacing compensation for market failures, existential threats and standard biographical problems become more and more replaced by so-called social ...
Jean-Michel Bonvin +3 more
doaj +2 more sources
Patterns of popular support for the welfare state: a comparison of the United Kingdom and Germany [PDF]
, 2001 This paper deals with the problems of social acceptance and social support of the welfare state. It starts with a brief presentation of approaches which infer in an immediate way from the self-interest of the citizens as welfare beneficiaries ...
Mau, Steffen
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Rethinking Nudge: Not One But Three Concepts [PDF]
, 2017 Nudge is a concept of policy intervention that originates in Thaler and Sunstein's (2008) popular eponymous book. Following their own hints, we distinguish three properties of nudge interventions: they redirect individual choices by only slightly ...
Cozic, Mikael, Mongin, Philippe
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The Ruins of the British Welfare State
Footprint, 2011 The subjects of Owen Hatherley’s A Guide to the New Ruins of Great Britain are architecture and urban development. The book addresses also some broader cultural, political and economic references, as well as personal anecdotes and memories.
Tahl Kaminer
doaj +1 more source