Results 21 to 30 of about 105,831 (302)

Social Policy Reform in Albania Stuck in Transition

Studia Universitatis Babes-Bolyai Sociologia, 2022
This article provides an analysis of social policy regarding social protection of vulnerable groups in Albania, by screening whether the welfare state has responded to the varying needs of socially excluded citizens.
Poni Merita
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Teamwork and use of teams in services for older people: a qualitative study of finnish nurse managers’ experiences

BMC Nursing
Background In Finnish services for older people, teams (a permanent group with a common task, divided for example by geographical or spatial criteria) have been implemented with the goal of improving the quality of care, individualized care and ...
Henrika Karhulahti-Nordström, Visa Väisänen, Saukkonen Petra, Alastalo Hanna, Timo Sinervo   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Victim Support in a Changing Welfare State

Social Work and Society, 2007
This article discusses how new kinds of individual needs develop parallel to the changes in the welfare state. From a study of Victim Service in Sweden it is shown how this organisation has grown parallel to the changes in the welfare state.
Kerstin Svensson
doaj   +4 more sources

Unmet need for healthcare services among unemployed people – findings from a national survey in Finland

BMC Health Services Research
Background Unemployed people have higher morbidity compared to employed people. Both the frequent use and the underutilization of healthcare services are common among unemployed people, potentially leading to unmet healthcare needs.
Hanna Rinne, Ari-Pekka Sihvonen, Visa Väisänen, Lars Leemann, Anna-Mari Aalto   +4 more
doaj   +1 more source

Bacteriophages and the immune system of the macroorganism

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Due to the emergence of antibiotic-resistant strains of bacteria in recent years, the treatment and prevention of various infections with bacteriophages have again become an important area of research.
I. A. Ivanovа, A. A. Trufanova, A. V. Filippenko, I. A. Bespalova, N. D. Omelchenko   +4 more
doaj   +1 more source

Whatever Works [PDF]

SSRN Electronic Journal, 2010
AbstractThe chapter compares employment structures in five Continental European welfare states, with a focus on private services. Despite a common trend to overcome institutional employment barriers by creating a more divided labor market, a closer look reveals considerable differences between national patterns of standard and non-standard work.
Eichhorst, Werner, Marx, Paul
openaire   +4 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source