Results 21 to 30 of about 1,221,165 (304)

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim   +8 more
wiley   +1 more source

Social Policy Reform in Albania Stuck in Transition

open access: yesStudia Universitatis Babes-Bolyai Sociologia, 2022
This article provides an analysis of social policy regarding social protection of vulnerable groups in Albania, by screening whether the welfare state has responded to the varying needs of socially excluded citizens.
Poni Merita
doaj   +1 more source

Book review: All our welfare: towards participatory socialpolicy by Peter Beresford [PDF]

open access: yes, 2016
As the UK welfare state comes under increased pressure, in All Our Welfare: Towards Participatory Social Policy, Peter Beresford offers a critique of its past, present and future from a participatory perspective.
Desai, Ashwin
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Evaluation of the Intensity of Post-Vaccination Immunity to Hepatitis B among HIV-infected and Conditionally Healthy Persons in Western Siberia

open access: yesЭпидемиология и вакцинопрофилактика
Relevance. Hepatitis B often causes liver cirrhosis and hepatocellular carcinoma, especially among patients with HIV. Vaccination is the main prophylaxis of HBV for preventing infection and developing chronic disease.
M. Yu. Kartashov   +5 more
doaj   +1 more source

Welfare service centers: Maintenance, repair, and care at the analog interfaces of the digital welfare state

open access: yesNew Media & Society, 2023
Many public administrations advocate digital services that allow for the deployment of algorithmic automation and the use of artificial intelligence. This shift has been discussed as the expansion of the digital welfare state. However, numerous citizens remain excluded from digital services provided by the state.
Anne Kaun, Agnes Liminga
openaire   +3 more sources

Fiscal sustainability in a new Keynesian model [PDF]

open access: yes, 2012
Recent work on optimal monetary and fiscal policy in New Keynesian models suggests that it is optimal to allow steady-state debt to follow a random walk.
Barro Robert J.   +4 more
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Welfare to Temporary Work: Implications for Labor Market Outcomes [PDF]

open access: yes, 2002
Recent welfare reforms are prompting some state and local welfare agencies to use temporary help service firms to help place welfare recipients into jobs.
Heinrich, Carolyn J.   +2 more
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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