Results 61 to 70 of about 92,943 (256)
Based on phylogenetic analysis of whole-genome sequencing of Yersinia pestis 2.MED1 strains of the medieval biovar, combined with epizootic, epidemiological, and climatic data over a 100-year period, we have reconstructed the most probable directions of ...
Galina A. Eroshenko +9 more
doaj +1 more source
Regional disparities in health services provision in the European Union.
Services of general interest (SGI) contribute to the European Union’s objectives, being fundamental to territorial cohesion and convergence, with a preeminent role in rural and peripheral territories.
Pedro Franco, Eduarda Marques da Costa
doaj
PECULIARITIES OF ACUTE RESPIRATORY DISEASES IN PATIENTS WITH ATOPY
In the work identified clinical and immunological characteristics of the course of ARVI patients with atopy and assessed the clinical efficacy of transfer factor in patients with severe immune deficiency.
L. O. Ponezheva +2 more
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Renegotiating Social Citizenship – Democracy in Welfare Service States
Welfare states are subject to constant change. Societal and political changes in recent decades have made social services increasingly crucial in the provision of welfare. Such conversions in the welfare architecture are not remaining without implications for the citizens concerned.
openaire +3 more sources
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
The article shows how personalisation in the UK has become part of a particular public service reform trajectory, in which it is argued that the threat of an ageing population makes it imperative to transform public services if the welfare state is not ...
Karen West, Anna Sofia Lundgren
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The risks of healthcare-associated infections in healthcare settings of the Rostov region
Objective: to analyze the incidence of healthcare-associated infections (HAIs) in healthcare settings of the Rostov region and the risks of their occurrence in order to develop proposals for improving the complex of anti-epidemic and preventive measures ...
S. A. Nenadskaya +9 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source

