Results 31 to 40 of about 181,509 (264)

Standardized Flexibility: The Choreography of ICT in Standardization of Service Work

Culture Unbound: Journal of Current Cultural Research, 2013
This article is based on a research project that explores the proliferation of information and communication technology (ICT) in public services. Furthermore, the research explores how the enhanced presence of ICT relates to efforts to increas-ingly ...
Maria Røhnebæk
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Motivations for Herbal Medicine use During Pregnancy and Childbirth in Butiama District, Tanzania: A Phenomenological Qualitative Study

Health Science Reports
Background and Aims Herbal medicine remains a popular choice among rural pregnant women in Tanzania, despite the availability of modern antenatal care.
Magnus Michael Sichalwe, Shadya Ramadhan mhinte, Regnald Raymond Kimaro   +2 more
doaj   +1 more source

Privatisation, Welfare Services and Welfare

, 1993
Interest in the subject of privatisation in Australia has increased markedly over recent years, although references to it have been made in the literature intermittently over a longer period. The original purpose of this bibliography was to record items dealing with the privatisation of welfare services.
openaire   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

PRRS management by European swine veterinarians: a descriptive insight into practices and profiles

Porcine Health Management
Background Despite extensive research on porcine reproductive and respiratory syndrome virus (PRRSV), herd-level management strategies vary considerably according to geographical area and depend significantly on many factors.
Charlotte Teixeira Costa, Arnaud Lebret, Stéphanie Bougeard, Nicolas Rose   +3 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Prevalence and factors associated with medication adherence among diabetes patients in rural sub-district health facilities in Bangladesh

Discover Public Health
Introduction Medication adherence is critical for improving chronic disease outcomes, particularly diabetes mellitus. The prevalence of medication adherence among people with diabetes in rural communities is largely unknown.
Imran Hossain Monju, Tanvir Ahmed, Moaz Abrar, Md Ahashan Habib, Fahmida Faiza, Mohammad Delwer Hossain Hawlader, Mohammad Rashidul Hashan   +6 more
doaj   +1 more source

The 2021 extreme rainfall in Gävle, Sweden: impacts on municipal welfare services and actions towards more resilient premises and operations

Hydrology Research
Climate-related risks, vulnerabilities, and impacts are increasing in cities, illustrated by precipitation-driven pluvial floods. Post-event analyses can aid in reducing urban flood risks, but knowledge gaps exist regarding how welfare services and ...
Erik Glaas, Mattias Hjerpe, Sofie Storbjörk   +2 more
doaj   +1 more source