Results 41 to 50 of about 189,275 (262)

Prevalence and factors associated with medication adherence among diabetes patients in rural sub-district health facilities in Bangladesh

Discover Public Health
Introduction Medication adherence is critical for improving chronic disease outcomes, particularly diabetes mellitus. The prevalence of medication adherence among people with diabetes in rural communities is largely unknown.
Imran Hossain Monju, Tanvir Ahmed, Moaz Abrar, Md Ahashan Habib, Fahmida Faiza, Mohammad Delwer Hossain Hawlader, Mohammad Rashidul Hashan   +6 more
doaj   +1 more source

Pathways into the labour market for Norwegians with mobility disabilities

Scandinavian Journal of Disability Research, 2010
This article explores pathways into working life for Norwegians with mobility disabilities through a life span approach. Semi-structured interviews were used to gather data from 15 employed individuals with mobility disabilities to gain an insight into ...
Janikke Solstad Vedeler, Svein Mossige
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Affordances of Welfare Services – Perspectives of Young Clients

Nordisk Välfärdsforskning, 2017
In Nordic welfare states, the indications of the social exclusion of young adults are addressed with measures and services aimed at getting them back on the «right» track.
Sanna Aaltonen, Päivi Berg, Sakari Karvonen   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Unmet need for healthcare services among unemployed people – findings from a national survey in Finland

BMC Health Services Research
Background Unemployed people have higher morbidity compared to employed people. Both the frequent use and the underutilization of healthcare services are common among unemployed people, potentially leading to unmet healthcare needs.
Hanna Rinne, Ari-Pekka Sihvonen, Visa Väisänen, Lars Leemann, Anna-Mari Aalto   +4 more
doaj   +1 more source

Excluded Youth in Iceland, the Faroe Islands and Norway

Nordisk Välfärdsforskning, 2017
In the Nordic countries, there are increasing concerns for the growing number of young people who are in neither education nor employment who are simultaneously struggling with mental health issues.
Cecilie Høj Anvik, Ragnhild Holmen Waldahl   +1 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Should GPs ask patients about their financial concerns? Exploration through collaborative research

Scandinavian Journal of Primary Health Care, 2020
Objective: Health services should arguably be concerned about the financial situation of patients since health problems can cause financial concerns, which in turn can cause health problems. In this study, we explored the role of the general practitioner
Solveig Osborg Ose, Live Standal Bøyum, Silje Lill Kaspersen, Arman Vestad, Per-Arne Gjelsvik   +4 more
doaj   +1 more source