Results 41 to 50 of about 181,509 (264)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Welfare Service for Employes [PDF]

open access: yesThe ANNALS of the American Academy of Political and Social Science, 1917
n ...
openaire   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Ethical Implications of AI‐Driven Chatbots in Domestic Violence Support

open access: yesSocial Inclusion
Our study explored the opportunities, challenges, and ethical considerations of using artificial intelligence (AI)‐driven chatbots in domestic violence (DV) support. DV is a serious public health and social problem. Identifying it as early as possible is
Hanna Mielismäki, Marita Husso
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Accessibility to Welfare Services and Communities: Enabling Integration and Human Rights

open access: yesSocial Inclusion
This thematic issue discusses the accessibility of welfare services and communities, emphasising its role in enabling integration and the realization of human rights.
Suvi Raitakari   +2 more
doaj   +1 more source

Is transition support a hurdle to getting a job?

open access: yesScandinavian Journal of Disability Research, 2014
This article investigates the impact of school to work transition support for young disabled adults. We specifically examine the claims of what we have termed the ‘hurdle theory’ of transition support, which dominates Norwegian disability research.
Sveinung Legard   +2 more
doaj   +1 more source

Should GPs ask patients about their financial concerns? Exploration through collaborative research

open access: yesScandinavian Journal of Primary Health Care, 2020
Objective: Health services should arguably be concerned about the financial situation of patients since health problems can cause financial concerns, which in turn can cause health problems. In this study, we explored the role of the general practitioner
Solveig Osborg Ose   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

On the Dynamic Relationships between the Non-profit and Public Providers of Welfare Services in European Union [PDF]

open access: yesTheoretical and Applied Economics, 2009
Economic activity in a mixed economy is shared among different kinds of organizations: private for-profit, private non-profit and governmental organizations, which are closely interdependent among them.
Helena Kuvíková, DomeNico Raguseo
doaj  

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