Results 111 to 120 of about 1,927,814 (300)

THE MODEL of SOCIAL STATE WELFARE [PDF]

open access: yesAnalele Universităţii "Constantin Brâncuşi" din Târgu Jiu: Seria Inginerie, 2019
The European Community Member State shall establish its own social policy which is aimed at better use of productive capacity by increasing employment.
Amelia Georgiana Boncea
doaj  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Incentives in the Welfare State [PDF]

open access: yes
This paper deals with economic incentives and welfare-state arrangements in OECD countries; it also offers some lessons for would-be welfare states. These arrangements differ, of course, among OECD countries. In particular, there is wide variation in the
Lindbeck, Assar
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The welfare state and privatization [PDF]

open access: yes, 2008
The “Great Capitalist Restoration” (Stanfield and Stanfield, 1996) from the 1970s/80s onward is predicated upon powerful convictions centring on economic efficiency and development, and the freedom and dignity of the individual.
McMaster, R.
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Federalism and the welfare state: The German case [PDF]

open access: yes
The comparative welfare state research regularly highlights 'federalism' as a factor that has delayed welfare state development and sets clear 'limits to welfare state growth'. Yet, apparently German federalism goes together with one of the most generous
Manow, Philip
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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