Results 141 to 150 of about 1,936,269 (327)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Exploring the Association between Welfare State and Mental Wellbeing in Europe: Does Age Matter? [PDF]
Int J Environ Res Public Health, 2022 Kalseth J +4 more
europepmc +1 more source
TRUE STATE DEPENDENCE IN MONTHLY WELFARE PARTICIPATION:A NONEXPERIMENTAL ANALYSIS [PDF]
This paper provides an empirical evaluation of true state dependence in welfare participation using unique administrative data from California that is measured at the monthly frequency, which coincides with the welfare eligibility period and so is free ...
Dean Hyslop +2 more
core
, 2002 A CCH policy brief investigating corporate welfare at the state and federal levels. Finds that taxpayer dollars supporting corporations that do not contribute to the public welfare might be better spent in addressing our nation's critical social issues ...
Les Brown
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Social and genetic associations with educational performance in a Scandinavian welfare state. [PDF]
Proc Natl Acad Sci U S A, 2022 Isungset MA +6 more
europepmc +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Long-Term Care and the State-Family Nexus in Italy and Japan-The Welfare State, Care Policy and Family Caregivers. [PDF]
Int J Environ Res Public Health, 2023 Miyazaki R.
europepmc +1 more source
The determinants of social spending in Spain (1880-1960): Is Lindert right? [PDF]
The main objective of this paper is to analyse the origins of the welfare state in Spain using the theoretical framework designed by Peter Lindert.
Margarita Vilar Rodriguez +1 more
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source