Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Raising the Floor? Genetic Influences on Educational Attainment Through the Lens of the Evolving Swedish Welfare State. [PDF]
Behav GenetPettersson O.
europepmc +1 more source
Decreasing Familial Welfare: The Fluid Welfare State in post-COVID Singapore
Hunter Ng
openalex +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Husbandry Conditions and Welfare State of Pet Chinchillas (Chinchilla lanigera) and Caretakers' Perceptions of Stress and Emotional Closeness to Their Animals. [PDF]
Animals (Basel)Gilhofer EM +6 more
europepmc +1 more source
Reproductive justice for the haunted Nordic welfare state: Race, racism, and queer bioethics in Finland. [PDF]
Bioethics, 2022 Sudenkaarne T, Blell M.
europepmc +1 more source
Welfare Packages and Staff Performance in Polytechnics in Anambra State South East, Nigeria
, 2023 Udemezue Annulika Ifeoma +2 more
openalex +1 more source
Introduction Special Issue “Paradoxical orders: Parenting encounters, the welfare state, and difference in Europe” [PDF]
, 2020 Anouk de Koning +2 more
openalex +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source