Results 151 to 160 of about 25,557,640 (287)

Assessing Well-being Using Hierarchical Needs [PDF]

open access: yes
well-being, Maslow, Southeast ...
Clarke, Matthew
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

PERSONAL WELL-BEING IN URBAN CHINA [PDF]

open access: yes
This paper reports the findings of a survey administering the Personal Well-Being Index in six Chinese cities (N=3390) to ascertain the personal well-being of China's urban population.The specific aims of the study were: (a) ascertain whether Chinese ...
Ingrid Nielsen   +2 more
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Wohlbefinden / Well-Being

open access: yes
Die Weltgesundheitsorganisation stellt einen engen Bezug zwischen Wohlbefinden und Gesundheit her. Hier wird der Frage nachgegangen, auf welche Weise beide definitorisch und empirisch verknüpft sind und welche Prozesse Wohlbefinden bedingen. Außerdem wird erläutert, welche an Personen gebundenen und kontextuellen Merkmale darauf Einfluss nehmen und wie
openaire   +1 more source

The online destination image as portrayed by the user-generated content on social media and its impact on tourists' engagement

open access: yesTourism & Management Studies
Tourism Destination Image (TDI) is complex, dynamic and multidimensional by nature and shaped by a multitude of events, interactions and sensory impressions, especially once the tourist is at the destination, generating tourists' engagement on social ...
Manuela Guerreiro   +9 more
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

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