Results 61 to 70 of about 3,301,048 (293)
Revisiting maximum-a-posteriori estimation in log-concave models [PDF]
, 2019 Maximum-a-posteriori (MAP) estimation is the main Bayesian estimation methodology in imaging sciences, where high dimensionality is often addressed by using Bayesian models that are log-concave and whose posterior mode can be computed efficiently by ...
Pereyra, Marcelo
core +2 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Applied Sciences, 2020 Initially, electrofacies were introduced to define a set of recorded well log responses in order to characterize and distinguish a bed from the other rock units, as an advancement to the conventional application of well logs.
Touhid Mohammad Hossain +3 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Revista Fuentes El Reventón Energético, 2019 The Analysis of the AVO attributes based on geophysics models, rock physics and seismic modeling, has become an important tool in the study of the exploration projects, helping to recognize zones with possible commercial interest.
Andres Eduardo Calle Ochoa +2 more
doaj
GeoresursyThe article considers facies analysis and the application of its results for the typification of rocks of the Tyumen Formation. The aim of the article is to create algorithms for the differentiated interpretation of geophysical studies of well log data ...
T. G. Isakova +13 more
doaj +1 more source
The evolution of HI and CIV quasar absorption line systems at 1.9 < z < 3.2
, 2013 We have investigated the distribution and evolution of ~3100 intergalactic HI absorbers with HI column densities log N(HI) = [12.75, 17.0] at 1.9 < z < 3.2, using 18 high resolution, high S/N quasar spectra obtained from the ESO VLT/UVES archive. We used
Carswell, Robert F. +3 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source