Results 91 to 100 of about 355,630 (305)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Experimental Study on Accurate Determination of Shale Porosity by Nuclear Magnetic Resonance

Chinese Journal of Magnetic Resonance
In recent years, the exploration and development of shale oil and gas have expanded significantly, accompanied by numerous challenges. Porosity is a fundamental parameter for shale reservoir evaluation and reserve estimation, providing essential data for
DU Qunjie
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Review and prospect of logging evaluation technologies for deep and ultra-deep clastic rocks

Youqi dizhi yu caishoulu
As oil and gas exploration advances to deep and ultra-deep layers， deep and ultra-deep clastic rocks face challenges such as complex wellbores and low signal-to-noise ratio of logging data under complex mud systems， which puts forward higher ...
YUAN Long, CAO Zhifeng, BIE Kang, GU Ming, CAO Yuan, CHEN Naidong, WU Siyi, XUE Hongbo, XU Yifan   +8 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

A simplified 3D finite difference method for electromagnetic logging while drilling simulation in symmetrical models

Frontiers in Earth Science
Electromagnetic (EM) Logging While Drilling (LWD) plays an increasingly significant role in oil and gas exploration and development. Fast and accurate simulation of EM LWD is essential for optimizing tool parameters and data processing.
Fengbo Li, Fengbo Li, Fengbo Li, Zhenguan Wu, Weining Ni, Weining Ni, Weining Ni, Xin Li, Xin Li, Xin Li, Xiaoqiao Liao, Hong Xiao, Yunxin Zeng   +12 more
doaj   +1 more source

Logging while drilling electromagnetic wave responses in inclined bedding formation

Petroleum Exploration and Development, 2019
For real-time inversion and fast reconstruction of formation true resistivity, the forward modeling of electromagnetic wave logging while drilling is usually based on the transversely isotropic formation model with vertical symmetry axis (VTI medium ...
Yiren FAN, Xufei HU, Shaogui DENG, Xiyong YUAN, Haitao LI   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Predicting density log from well log using machine learning techniques and heuristic optimization algorithm: A comparative study

Petroleum Research
In the petroleum industry, the analysis of petrophysical parameters is critical for efficient reservoir management, production optimization, development strategies, and accurate hydrocarbon reserve estimations.
Mehdi Rahmati, Ghasem Zargar, Abbas Ayatizadeh Tanha   +2 more
doaj   +1 more source