Results 81 to 90 of about 361,524 (357)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Energy-efficient off-body communication nodes with receive diversity [PDF]

, 2013
Off-body wireless communication applications range from fall-detection systems for the elderly to monitoring networks for rescue workers. Further development of practical body-worn systems requires compact, low-cost and low-power battery-powered ...
Moerman, Ingrid, Rogier, Hendrik, Van Torre, Patrick, Vanveerdeghem, Peter   +3 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

The Unified Logging Infrastructure for Data Analytics at Twitter

, 2012
In recent years, there has been a substantial amount of work on large-scale data analytics using Hadoop-based platforms running on large clusters of commodity machines. A less-explored topic is how those data, dominated by application logs, are collected
Lee, George, Lin, Jimmy, Liu, Chuang, Lorek, Andrew, Ryaboy, Dmitriy   +4 more
core   +3 more sources

Moving in a Hierarchized Landscape Changing Border Regimes in Central Kalimantan [PDF]

, 2011
Transnational mobility is a common feature among borderland communities. Central Borneo has been a relatively fluid and open riverine-based socio-cultural and economic space since the arrival of colonial states, without much interference from the ...
Lumenta, D. (Dave)
core   +3 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Downhole logging as a paeoceanographic tool on ocean drilling program leg 138: Interface between high-resolution stratigraphy and regional syntheses [PDF]

, 1992
On Ocean Drilling Program (ODP) Leg 138, standard shipboard procedures were modified to allow for the real-time monitoring of several laboratory core-scanning systems that provide centimeter-scale measurements of saturated bulk density, magnetic ...
Bloomer, Stephen F., Dadey, Kathleen A., Hagelberg, T. K., Lyle, Mitchell, Mayer, Larry A., Pisias, Nicklas G., Shipboard Scientific Party   +6 more
core   +4 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Gas content prediction model considering multi-factor coupling on shale by simplified local density model

Frontiers in Earth Science
The quantity of gas adsorbed by shale, typically quantified using the Langmuir equation in isothermal adsorption experiments, is a critical metric for evaluating the gas content and resource potential of shale formations.
Haomin Liu, Ran Zhang, Ran Zhang, Ruikang Cui   +3 more
doaj   +1 more source

Experimental Investigation on CO2 Injection in Block M

Journal of Chemistry, 2018
The purpose of this report was to perform an experimental evaluation of enhanced oil recovery (EOR) using CO2 injection. A slim tube test and PVT experiment are used to determine the minimum miscibility pressure as well as a few related physical ...
Peng Chen, Linlin Wang, Sidun Zhang, Junqiang Fan, Song Lu   +4 more
doaj   +1 more source