Results 111 to 120 of about 983,554 (294)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Log of books checked out by students, taught by Harry Bentley Wells at Manzanar High School

open access: yes, 1942
Log of books checked out by seventeen students for a course taught by Harry Bentley Wells at Manzanar High School. The authors include Jennie Hall, Beatty, Robinson, and Louise M. Mohr. Several of the names have been crossed out.
Wells, Harry Bentley: author
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Letter from H. Bentley Wells to Dr. Genevieve W. Carter, Superintendent of Education, January 14, 1943

open access: yes, 1943
Letter from Harry Bentley Wells to Genevieve W. Carter requesting he be considered for promotion to the vacant position of Acting Assistant Principal of the Manzanar Secondary School, sent on January 14, 1943.
Wells, Harry Bentley: author
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

[Decorated mortarboard belonging to Vanessa Wells]

open access: yes
Photograph of a mortarboard cap decorated and worn by Vanessa Wells in Spring 2025 commencement ...
Wells, Vanessa
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Syllabi for classes taught by Harry Bentley Wells at Manzanar High School

open access: yes, 1942
Syllabi for 7th Grade Social Living, Social Living: Grade Eight, Ninth grade social living, World History and Geography: Grade Ten, American Life and Institutions: Grade Eleven, 12th Grade Social Social Problems. Taught by Harry Bentley Wells at Manzanar
Wells, Harry Bentley: author
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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