Results 121 to 130 of about 1,154,769 (315)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Groundwater Storage Variations across Climate Zones from Southern Poland to Arctic Sweden: Comparing GRACE-GLDAS Models with Well Data

Remote Sensing
The aim of this paper is to assess the correlation of groundwater level changes (or groundwater level anomalies (GWLA)) obtained from direct measurements in wells with groundwater storage anomalies (GWSA) calculated using Gravity Recovery and Climate ...
Zofia Rzepecka, Monika Birylo, Jerker Jarsjö, Feifei Cao, Jan Pietroń   +4 more
doaj   +1 more source

HOW WELL DOES THE NSQIP SURGICAL CALCULATOR PREDICT EARLY ADVERSE OUTCOMES IN OLDER NON-CARDIAC SURGICAL PATIENTS WITH SELF-REPORTED LIMITATIONS IN MOBILITY? [PDF]

, 2015

openalex   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

IODP Expedition 325, Hole M0054B - Well Logging Data

, 2021
Jody M. Webster, Yusuke Yokoyama, Carol Cotterill, Louise Anderson, Sophie Green, Raphaël Bourillot, Juan C. Braga, André W. Droxler, T. M. Esat, Thomas Felis, Kazuhiko Fujita, Michael K. Gagan, Eberhard Gischler, E. Herrero‐Bervera, Hongchen, Jiang, Marc Humblet, Mayuri Inoue, Tania Lado Insua, Yasufumi Iryu, Luigi Jovane, Hironobu Kan, Braddock K. Linsley, Didier Loggia, Heath J. Mills, Donald C. Potts, Claire Seard, Atsushi Suzuki, Alexander Thomas, W. G. Thompson, Manish Tiwari, Alexander W. Tudhope   +30 more
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Knowing Well, Being Well: well-being born of understanding [PDF]

American Journal of Health Promotion, 2020
David L, Katz, Rebekah, Rollston, Sandro, Galea, Elizabeth Pegg, Frates, Tom, Rifai, Candace D, McNaughton   +5 more
openaire   +5 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source