Results 151 to 160 of about 2,737,894 (314)

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

open access: yesAdvanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha   +13 more
wiley   +1 more source

East-West Center review, Vol. 3 no. 2 (October 1966)

open access: yes, 1966
For more about the East-West Center, see http://www.eastwestcenter.org/Contents: Indians in Fiji and Japanese in Hawaii / Thomas E. Korson - Art and morality / Joseph J. Nagano - The Moon as a symbol in two Chinese and two English poems / Heng-Hsiung Jen
East-West Center Grantees' Association
core  

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

open access: yesAdvanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang   +12 more
wiley   +1 more source

The West Texan, May, 1970

open access: yes, 1970
This item is an issue of The West Texan from May ...
West Texas A&M University
core  

Biomimetic Ru‐Mn Nanozyme with Cascade Catalytic Activity Attenuates Secondary Brain Injury in Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan   +8 more
wiley   +1 more source

The West Texan, August, 1959

open access: yes, 1959
This item is an issue of The West Texan from August ...
West Texas A&M University
core  

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

open access: yesAdvanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi   +8 more
wiley   +1 more source

The West Texan, November, 1963

open access: yes, 1963
This item is an issue of The West Texan from November ...
West Texas A&M University
core  

Author Correction: Discovery of chirally dependent protein modifications by D- and L-2-hydroxyglutarates. [PDF]

open access: yesNat Chem
Zhang Z   +12 more
europepmc   +1 more source

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