Results 51 to 60 of about 24,959 (209)

Sensitivity Characteristics of Genotype 2 West Nile Virus Strains to Anti-Viral Drugs

Антибиотики и Химиотерапия
Background. Annual studies of West Nile virus (WNV) circulating in endemic areas are necessary to characterize its properties and track them over time.
E. A. Gusev, A. D. Romanovskaya, A. Yu. Galkina, D. N. Luchinin, E. V. Molchanova   +4 more
doaj   +1 more source

The Role of Birds as Potential Reservoirs of West Nile Virus in the Territory of the Russian Federation

Проблемы особо опасных инфекций, 2012
Submitted are the materials on epizootiology of West Nile Fever in birds, taking into account their migration. Described are the characteristics of WNF in wild and synanthropic birds.
A. A. Baturin, V. A. Antonov, V. P. Smelyansky, K. V. Zhukov, V. F. Chernobay, N. N. Kolyakina   +5 more
doaj   +1 more source

Immunological Interactions Between Gammadelta T Cells and West Nile Virus in the Infected Host

Reviews in Medical Virology, Volume 36, Issue 4, July 2026.
ABSTRACT Between mosquitoes and birds, West Nile virus (WNV) is a neurotropic flavivirus, an arthropod‐borne pathogen involved in an enzootic cycle. Additionally, it can infect both people and horses, leading to severe illness. Since 1999, WNV has spread across North and South America, including Mexico and the Caribbean.
E. Cimini, E. Tartaglia, F. Cristofanelli, S. Gili, F. Maggi   +4 more
wiley   +1 more source

Economic Cost Analysis of West Nile Virus Outbreak, Sacramento County, California, USA, 2005

Emerging Infectious Diseases, 2010
In 2005, an outbreak of West Nile virus (WNV) disease occurred in Sacramento County, California; 163 human cases were reported. In response to WNV surveillance indicating increased WNV activity, the Sacramento-Yolo Mosquito and Vector Control District ...
Loren M. Barber, Jerome J. Schleier, Robert K.D. Peterson   +2 more
doaj   +1 more source

Synthesis and Evaluation of Aromatic Sulfonamide and Disulfonamide Derivatives as Dengue Virus NS3–NS5 Interaction Inhibitors

ChemMedChem, Volume 21, Issue 11, 15 June 2026.
A synthetic methodology for the preparation of asymmetric benzene‐1,4‐disulfonamides was developed and applied to generate potential anti‐dengue virus (DENV) compounds. Guided by computer‐assisted structural rationalization, we designed synthetically more accessible analogs with reduced toxicity that interact with the DENV NS5 domain, thereby ...
Jakub Janáč, Jan Drahorád, Jakub Harvalík, Tereza Horáčková, Manfred Brinker, Arianna Loregian, Andrea Brancale, Beatrice Mercorelli, Petra Cuřínová   +8 more
wiley   +1 more source

ProTides for Antiviral Activity Beyond Liver Cells

Chemistry – A European Journal, Volume 32, Issue 21, 1 June 2026.
A strategy for obtaining prodrugs of antiviral nucleotides with broad tissue activity is presented that relies on cycloalkyl or cycloalkylalkyl esters, improving uptake and esterase cleavage, and producing nanomolar inhibitors in kidney, colon, and lung cells.
Felix Goebel, Adrian Humboldt, Heeyoung Kim, Carl J. M. Schölzel, Ralf Bartenschlager, Clemens Richert   +5 more
wiley   +1 more source

Peculiarities of Epidemiological Situation on the West Nile Fever in 2012 in the Territory of the Russian Federation

Проблемы особо опасных инфекций, 2013
During the epidemic season of 2012 453 cases of West Nile fever (WNF) were registered in the territory of the 21 constituent entities of the Russian Federation. Epidemic process is spreading itself towards the northern regions of Russia.
E. V. Putintseva, V. A. Antonov, D. V. Viktorov, V. P. Smelyansky, K. V. Zhukov, V. V. Manankov, N. I. Pogasy, G. A. Tkachenko, I. M. Shpak, E. A. Snatenkov   +9 more
doaj   +1 more source

Reverse Genetics of Orthoflaviviruses: Strategies for Constructing Functional or Infectious cDNA

Journal of Medical Virology, Volume 98, Issue 6, June 2026.
ABSTRACT Reverse genetics (RG) systems have transformed RNA virus research by enabling the recovery of recombinant viruses entirely from cloned cDNA. These platforms allow precise, hypothesis‐driven manipulation of viral genomes and support systematic phenotypic analyses in vitro and in vivo.
Young‐Min Lee
wiley   +1 more source

Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 6, Page 1212-1224, June 2026.
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley   +1 more source

Tick‐Tac‐Foe: When Ticks, Trade, and Zoonotic Pathogens Align in African Wet Meat Markets

Public Health Challenges, Volume 5, Issue 2, June 2026.
ABSTRACT Zoonotic diseases account for over ∼60% of infectious diseases and present a significantly growing fatality threat in Africa. Live and wet markets (LWMs) in Africa function as key economic venues that support human livelihoods through social interaction and trade in food stuff, including meat and other animal‐based products.
Allen Takudzwa Munaro
wiley   +1 more source