Results 61 to 70 of about 2,326,098 (203)
During the epidemic season of 2012 453 cases of West Nile fever (WNF) were registered in the territory of the 21 constituent entities of the Russian Federation. Epidemic process is spreading itself towards the northern regions of Russia.
E. V. Putintseva +9 more
doaj +1 more source
Ligand‐based virtual screening of over five million compounds identifies a thienopyrimidinone hit as a novel allosteric nSMase2 modulator. Structure‐guided optimisation improves inhibitory potency and delivers derivatives with antiviral activity against West Nile virus, expanding the chemical space of nSMase2 inhibitors and supporting host‐directed ...
Hadrián Álvarez‐Fernández +6 more
wiley +1 more source
This paper describes the outbreak of West Nile fever in the Rostov Region in 2010 and evaluates its ecological and epidemiological peculiarities. From 15th of July till 22nd of September 2010, detected were the 64 cases (1, 4800/0000) of the disease ...
E. A. Moskvitina +15 more
doaj +1 more source
West Nile fever is a mosquito-borne febrile illness seen in Africa, Asia, and Europe, but reported in North America only once. West Nile virus is of the family Flaviviridae, genus Flavivirus. Several West Nile fever outbreaks were reported from Israel in the 1950s and in 1980.
Nancy, Delgado-López +3 more
openaire +1 more source
UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro +7 more
wiley +1 more source
Outbreak of West Nile virus causing severe neurological involvement in children, Nuba Mountains, Sudan, 2002. [PDF]
An atypical outbreak of West Nile virus (WNV) occurred in Ngorban County, South Kordophan, Sudan, from May to August 2002. We investigated the epidemic and conducted a case-control study in the village of Limon.
Depoortere, E +5 more
core +1 more source
ABSTRACT Tick‐borne filarial nematodes are a complex and understudied group of parasites that rely on ticks for transmission in vertebrates. This review examines how intrinsic and extrinsic factors may influence the successful transmission of filarial nematodes in tick vectors, drawing insights from extensively studied haematophagous dipteran vector ...
Oluwaseun D. Ajileye +4 more
wiley +1 more source
West Nile Virus (WNV) fact sheet [PDF]
West Nile virus infection can cause serious disease. WNV is established as a seasonal epidemic in North America that flares up in the summer and continues into the fall.
core +2 more sources
Within the period of 2000-2011, in the West of Kazakhstan, identified have been five, previously unknown in the territory, natural foci of dangerous infectious diseases such as hemorrhagic fever with renal syndrome, Astrakhan spotty fever, Crimean ...
A. K. Grazhdanov +7 more
doaj +1 more source
Substance P and NK‐1R in Dengue: A First Serological Investigation
ABSTRACT Background Dengue fever lacks reliable biomarkers to explain its complex pathophysiology. Substance P (SP) and its receptor, the Neurokinin‐1 receptor (NK1R), known regulators of inflammation and vascular permeability in viral infections, may play a role in dengue but remain unexplored. Aim/Objective To investigate the levels of SP and NK1R in
Riffat Mehboob +7 more
wiley +1 more source

