Results 71 to 80 of about 253,687 (260)

Relationships among tissues, biofluids, and otolith selenium concentrations in wild female burbot (Lota lota)

open access: yesIntegrated Environmental Assessment and Management, EarlyView., 2023
Abstract In the Lake Koocanusa‐Kootenai River system (Montana, USA and British Columbia, Canada), selenium (Se) contamination has become an international concern and is suspected to contribute to the observed burbot (Lota lota) population collapse. Due to our limited ability to sample burbot in Lake Koocanusa for monitoring studies, we used a reference
Stephanie D. Graves   +6 more
wiley   +1 more source

Precision‐Engineered Silver Single‐Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury

open access: yesAdvanced Science, EarlyView.
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang   +10 more
wiley   +1 more source

West Syndrome in an Infant With Vitamin B12 Deficiency Born to Autoantibodies Positive Mother

open access: yesFrontiers in Pediatrics, 2019
Infantile vitamin B12 deficiency, a rare nutritional disorder in developed countries, is characterized by megaloblastic anemia and non-specific symptoms, including failure to thrive, hypotonia, and seizure.
Pin Fee Chong   +6 more
doaj   +1 more source

A Sirtuin‐1‐Targeted Gene‐Activating Tetrahedral DNA Attenuates Bladder Fibrosis by Restoring Mitophagy in Fibroblasts via the SIRT1‐FOXO3‐BNIP3 Axis

open access: yesAdvanced Science, EarlyView.
The SIRT1‐targeted saRNA‐delivering tetrahedral DNA (TSA) treatment effectively upregulates SIRT1 expression, which subsequently promotes FOXO3A deacetylation. This deacetylation event relieves FOXO3A's transcriptional repression on the BNIP3 gene, thereby initiating PINK1‐PARKIN‐dependent mitophagy.
Wei Wang   +10 more
wiley   +1 more source

Low-Dose ACTH Therapy for Infantile Spasms

open access: yesPediatric Neurology Briefs, 1999
The lowest effective ACTH dose, with fewest adverse effects, for the treatment of West syndrome (WS) was determined in a comparative, randomly assigned, controlled study involving 25 patients with cryptogenic (CWS, n=9) or symptomatic (SWS, n=16) WS, at ...
J Gordon Millichap
doaj   +1 more source

Effect Differences of Omega‐3 Fatty Acids From Plant Oil and Fish Oil on Human Health

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Omega‐3 fatty acids in plant oil is no less than fish oil on human health. ALA in plant oil takes directly healthy effects without conversion to DHA and EPA. Plant oil can be substitutes for fish oil to support partial ω‐3 fatty acids. For people who cannot afford fish oil, plant oil is also good for public health.
Mengxue Fang   +3 more
wiley   +1 more source

Visual Attention in West Syndrome

open access: yesPediatric Neurology Briefs, 2002
The maturation of visual attention is evaluated prospectively in a study of infants with West syndrome (WS) before, during and after the onset of seizures, followed until age 24 +/- 2 months at Catholic University, Rome, and University of Pisa, Italy.
J Gordon Millichap
doaj   +1 more source

Combination Therapy With Vigabatrin and Prednisolone Versus Vigabatrin Alone for Infantile Spasms

open access: yesAnnals of Clinical and Translational Neurology
Objective The study evaluated the effectiveness of combination therapy with vigabatrin and prednisolone versus vigabatrin alone for treating infantile epileptic spasms syndrome (IESS).
Rachata Boonkrongsak   +6 more
doaj   +1 more source

Genetic and Phenotypic Features of the Five Known Polyaminopathies: A Critical Narrative Review

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Polyaminopathies are a recently described family of rare genetic neurodevelopmental disorders. Polyaminopathies disrupt the biosynthesis of the primary polyamines: putrescine, spermidine, and spermine. Snyder–Robinson syndrome results from hemizygous loss‐of‐function variants in the spermine synthase (SMS) gene, resulting in decreased or ...
Elizabeth A. VanSickle   +26 more
wiley   +1 more source

West syndrome: ethiology, management, long-term outcomes

open access: yesБюллетень сибирской медицины, 2009
The article is based on long-term observation of 27 patients with West syndrome, age of onset, etiology of symptomatic forms, neurological status, efficiency of hormone therapy and antiepileptic drugs.
L. S. Krayeva   +2 more
doaj   +1 more source

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