Results 61 to 70 of about 268,123 (292)
Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities
Advanced Science, EarlyView.ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal +3 more
wiley +1 more source
Prolonged EEG Depression as a Predictor of West Syndrome in Term Infants with HIE
Pediatric Neurology Briefs, 2011 Seventeen term and near-term infants with hypoxic ischemic encephalopathy (HIE) were studied at Okazaki City Hospital and other centers in Japan to clarify the relationship between prolonged depression of the EEG and later development of West syndrome ...
J Gordon Millichap
doaj +1 more source
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
A Novel PAFAH1B1 Splicing Variant Identified in a Patient with Classical Lissencephaly
Tokyo Women's Medical University Journal, 2020 Lissencephaly is a severe brain malformation associated with abnormal formation of cerebral sulci. Until now, many genes related to lissencephaly have been identified.
Tomoe Yanagishita +5 more
doaj +1 more source
Temporal Interference Stimulation Enhances Neural Regeneration
Advanced Science, EarlyView.Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressotti +15 more
wiley +1 more source
Frontiers in Psychology, 2018 HighlightsThe kinematics of hand movements (spatial use, curvature, acceleration, and velocity) of infants with their mothers in an interactive setting are significantly associated with age in cohorts of typical and at-risk infantsdiffer significantly at
Lisa Ouss +15 more
doaj +1 more source
Advanced Science, EarlyView.Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan +11 more
wiley +1 more source
Factors influencing the evolution of West syndrome to Lennox-Gastaut syndrome
, 2009 This study examines factors influencing the evolution of West syndrome to Lennox-Gastaut syndrome. The study population comprised 98 patients diagnosed with West syndrome and monitored for at least 3 years.
김흥동, 강훈철
core +1 more source
Causal‐Guided Ultra‐Long‐Term Time Series Forecasting Via Anticipated Covariates
Advanced Science, EarlyView.Often treated as unknown, information from the future remains underutilized.We demonstrate that in a coupled dynamical system, providing the future state of the effect enables accurate forecasting of the cause for a long timesteps. A time series forecasting paradigm that introduces anticipated covariates to represent such known future states is ...
Jintong Zhao +4 more
wiley +1 more source
Clustered Tonic Spasms Developed after Disappearance of Hypsarrythmia in West Syndrome
, 2007 We report an infant case of West syndrome with clustered tonic spasms seen after the disappearance of hypsarrythmia. This time lag until the development of tonic spasms implies that their development is not directly related to hypsarrythmia.
Imataka, George +6 more
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