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Evaluating the Influence of Rosemary Leaves Extract on Hormonal and Histopathological Alterations in Male Rabbits Exposed to Cypermethrin [PDF]
Archives of Razi Institute, 2023 Rosemary Leaves (Rosmarinus officinalis) gained importance as natural antioxidants which strengthen the endogenous antioxidant defenses through die. The present experience was designed to assess the protective effect of ethanolic extract of rosemary ...
S Ali Hasan, A. A Al-Rikaby
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Çocuk Dergisi, 2022 Objective: West syndrome is the most common infantile epileptic encephalopathy, and ACTH or oral corticosteroids are frequently used in its treatment. The aim of this study was to evaluate the efficacy of ACTH therapy and its effects on bone metabolism ...
Mesut Güngör +5 more
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Journal of the Endocrine Society, 2021 Context The normal cortisol response 30 or 60 minutes after cosyntropin (ACTH[1–24]) is considered to be ≥18 μg/dL (500 nmol/L). This threshold is based on older serum cortisol assays.
B. Javorsky +6 more
semanticscholar +1 more source
Frontiers in Endocrinology, 2016 Adrenocorticotropin (ACTH) acts via a highly selective receptor that is a member of the melanocortin receptor subfamily of type 1 G protein-coupled receptors. The ACTH receptor, also known as the melanocortin 2 receptor (MC2R), is unusual in that it is absolutely dependent on a small accessory protein, melanocortin receptor accessory protein (MRAP) for
Clark, AJ +6 more
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Stress, 2023 Hypothalamic-pituitary-adrenal (HPA) axis dynamics are disrupted by opioids and may be involved in substance abuse; this persists during withdrawal and abstinence and is associated with co-morbid sleep disruption leading to vulnerability to relapse.
Hershel Raff +4 more
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Proceedings of the National Academy of Sciences, 1974 Structural modifications within the active site of the ACTH molecule have produced analogs that inhibit the hormone sensitive adenylate cyclase system of bovine adrenal cortical plasma membranes. It is demonstrated that the tryptophan residue of the ACTH molecule is essential for stimulation of the enzyme.
K, Hofmann, J A, Montibeller, F M, Finn
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Indian Journal of Neurosurgery, 2020 ACTH secreting pituitary adenomas are rare occurrences in autoptical, surgical and neuroradiological series. We herewith describe a series of four patients of Cushing’s disease due to ACTH secreting pituitary microadenoma.
Ashok Gandhi +3 more
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Dynamics of ACTH and Cortisol Secretion and Implications for Disease
Endocrine reviews, 2020 The past decade has seen several critical advances in our understanding of hypothalamic–pituitary–adrenal (HPA) axis regulation. Homeostatic physiological circuits need to integrate multiple internal and external stimuli and provide a dynamic output ...
S. Lightman +2 more
semanticscholar +1 more source
Effect of adrenocorticotropic hormone infusion on circulating sclerostin levels
Endocrine Connections, 2021 Glucocorticoid use is the most common cause of secondary osteoporosis. Poor skeletal health related to glucocorticoid use is thought to involve inhibition of the Wnt/β-catenin signaling pathway, a key pathway in osteoblastogenesis.
Sarah Zaheer +8 more
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Primary adrenal insufficiency - Addison's disease
Journal of Education, Health and Sport, 2022 Introduction and purpose Addison's syndrome is defined as primary adrenal insufficiency, the symptoms of which result from hormonal deficiencies: glucocorticosteroids, mineralocorticosteroids and androgens.
Jakub Metelski +4 more
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