Results 11 to 20 of about 71,688 (285)
Frontiers in Endocrinology, 2016 Adrenocorticotropin (ACTH) acts via a highly selective receptor that is a member of the melanocortin receptor subfamily of type 1 G protein-coupled receptors.
Hussain, M +14 more
core +6 more sources
ACTH precursors characterize the ectopic ACTH syndrome
Clinical Endocrinology, 1994 Objective - ACTH is secreted by the pituitary following processing of larger molecular weight precursors, proopiomelanocortin and pro-ACTH. Ectopic ACTH syndrome refers to the secretion of ACTH by non-pituitary tumours, but the predominant circulating ...
White, A.; id_orcid +19 more
core +6 more sources
Proceedings of the National Academy of Sciences, 1974 Structural modifications within the active site of the ACTH molecule have produced analogs that inhibit the hormone sensitive adenylate cyclase system of bovine adrenal cortical plasma membranes. It is demonstrated that the tryptophan residue of the ACTH molecule is essential for stimulation of the enzyme.
K, Hofmann, J A, Montibeller, F M, Finn
openaire +2 more sources
Disease Models & Mechanisms, 2020 X-linked infantile spasms syndrome (ISSX) is a clinically devastating developmental epileptic encephalopathy with life-long impact. Arx(GCG)10+7, a mouse model of the most common triplet-repeat expansion mutation of ARX, exhibits neonatal spasms ...
Meagan S. Siehr +2 more
doaj +1 more source
Gel chromatographic characterization of immunoreactive adrenocorticotropin in patients with ACTH hypersecretion [PDF]
, 1989 We investigated the molecular size of circulating immunoreactive ACTH by gel chromatography in patients with ACTH hypersecretion due to various disorders of the hypothalamic-pituitary-adrenal axis.
Winkelmann, W. +3 more
core +1 more source
Inconsistent stimulation of plasma ACTH through corticotropin-releasing factor in a patient with central Cushing's disease due to pituitary adenoma [PDF]
, 1985 Three uncommon findings were observed in a case of Cushing's disease due to macroadenoma: no suppression of plasma ACTH during an 8-mg dexamethasone test, a negative corticotropin-releasing factor test, and a normal X-ray of the sella turcica.
Lüdecke, D. K. +5 more
core +1 more source
Veterinární Medicína, 2015 The hypothalamic-pituitary-adrenal axis (HPA) is a complex system regulated by multiple factors. Sexual dimorphism of this axis has been described in different species under physiological conditions and it has been proposed that sexual hormones could ...
M.F. Gallelli +6 more
doaj +1 more source
Gene array analysis of adrenal glands in broiler chickens following ACTH treatment [PDF]
, 2009 Difference in adaptability responses to stress has been observed amongst bird species, strains, and individuals. Components of the HPA axis, one of the internal systems involved in homeostasis re-establishment following stress, could play a role in this ...
Young Kyoung Park +13 more
core +1 more source
Does an Analysis of the Pulsatile Secretion Pattern of Adrenocorticotropin and Cortisol Predict the Result of Transsphenoidal Surgery in Cushing’s Disease. [PDF]
, 1993 The endocrinological, surgical, and histological findings of patients with ACTH-dependent Cushing's disease were correlated with the pulsatile secretion pattern of ACTH and cortisol and the outcome after transsphenoidal pituitary surgery.
Brabant, Georg +5 more
core +1 more source
The effect of sodium valproate in Cushing's disease, Nelson's syndrome and Addison's disease [PDF]
, 1988 We investigated the effect of sodium valproate on plasma ACTH and serum cortisol concentrations in different pathological states of ACTH hypersecretion.
Winkelmann, W. +4 more
core +1 more source