Results 161 to 170 of about 641,559 (279)

Crossing barriers: the burden of inflammatory bowel disease across Western Europe. [PDF]

Ther Adv Gastroenterol, 2023
Kumar A, Yassin N, Marley A, Bellato V, Foppa C, Pellino G, Myrelid P, Millan M, Gros B, Avellaneda N, Catalan-Serra I, El-Hussuna A, Cunha Neves JA, Roseira J, Cunha MF, Verstockt B, Bettenworth D, Mege D, Brookes MJ.   +18 more
europepmc   +1 more source

Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk

Advanced Science, EarlyView.
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang, Hui Geng, Zhengyan Yao, Yuan Jiang, Can Chen, Zequn Lu, Shuangshuang Tian, Ming Zhang, Ruiyan Liu, Chenxi Feng, Bin Li, Xiaoping Miao, Jianbo Tian, Shaokai Zhang, Ying Zhu   +14 more
wiley   +1 more source

Coupled Above‐ and Belowground Ecosystem Stability Worldwide

Advanced Science, EarlyView.
Are the worlds above and below our feet in sync? This global exploration reveals an entangled fate between above‐ and belowground ecosystem stability. It identifies arid regions as hotspots for this coupling and highlights temperature stability as a vital safeguard for maintaining ecosystem balance across our warming planet.
Zexin Meng, Huiwen Li, Yiping Wu, Peter B. Reich, Nico Eisenhauer, Diego Abalos, Daniel Revillini, Shuguang Liu, Wende Yan, Ji Chen, Alexey Voinov, Zhifeng Yang, Ying‐Ping Wang, Fubo Zhao, Linjing Qiu, Jingfeng Xiao, Shantao An, Guopeng Liang, Manuel Delgado‐Baquerizo   +18 more
wiley   +1 more source

Metagenomic survey reveals Volzhskoe tick virus in <i>Hyalomma</i> ticks for the first time in western Europe, North-Eastern Spain. [PDF]

One Health
Carrera-Faja L, Jasso MV, Sarmiento I, Cabrera-Gumbau JM, Espunyes J, Martínez-Urtaza J, Cabezón O.   +6 more
europepmc   +1 more source

The Genomics of Isolated Populations of Gampsocleis glabra (Orthoptera: Tettigoniidae) in Central and Western Europe. [PDF]

Insects, 2023
Hawlitschek O, Bruns C, Dey LS, Nuhlíčková S, Felix R, van Kleef H, Nakel J, Husemann M.   +7 more
europepmc   +1 more source

Efficiency, distortions and factor utilization during the interwar period [PDF]

In this paper, we analyze the International Great Depression in the US and Western Europe using the business cycle accounting method a la Chari, Kehoe and McGrattan (CKM 2007).
Klein , Alexander, Otsuy, Keisuke
core  

Multicohort Validation of Gut Microbiome Signatures for Cholangiocarcinoma Diagnosis and Functional Characterization of Bifidobacterium Pseudocatenulatum

Advanced Science, EarlyView.
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao, Jianwen Jiang, Ruiqing Zhang, Dongya Zhang, Chenchen Zhang, Ang Li, Haifeng Lu, Hua Zhang, Lin Zhou, Wenzhi Guo, Peihao Wen, Jianfeng Xue, Jie Pan, Tuerganaili Aji, Zhou Lan, Xianzhi Jiang, Shusen Zheng, Zujiang Yu, Zhigang Ren   +18 more
wiley   +1 more source

Impact of Environmental Factors on the Distribution Patterns of Nephropathia Epidemica Cases in Western Europe. [PDF]

Environ Health Perspect
Erazo D, Vincenti-Gonzalez MF, Ghisbain G, Faber M, Reusken C, Sauvage V, Wint W, Leirs H, Dellicour S, Tersago K.   +9 more
europepmc   +1 more source

Intracellular Aβ42 Sequestration by a Serine Protease Mitigates Neurotoxicity in a Drosophila Alzheimer's Disease Model

Advanced Science, EarlyView.
Emerging evidence suggests that intraneuronal Aβ accumulation represents an early pathogenic event in Alzheimer's disease (AD). Using Drosophila AD model, this study shows that a nonsecreted serine protease Yip7 physically interacts with Aβ. This causes intraneuronal Aβ accumulation but surprisingly reduces the associated neurotoxicity, arguing that ...
Jingyun Su, Meng Yang, Xinfeng Wang, Pa Wu, Zongzhao Zhai   +4 more
wiley   +1 more source

Trends in myopia prevalence and projected visual impairment in Western Europe: a pooled analysis of Dutch population-based cohorts (1900-2000). [PDF]

BMJ Public Health
Kneepkens S, Enthoven CA, Polling JR, de Vries VA, Tideman JWL, Klaver C, Eye Epidemiology research group.   +6 more
europepmc   +1 more source