A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Breeding for culinary and nutritional quality of common bean (Phaseolus vulgaris L.) in intercropping systems with maize (Zea mays L.) [PDF]
Common bean (Phaseolus vulgaris L.) is widely intercropped with maize (Zea mays L.) in the North of Spain. Breeding beans for multiple cropping systems is important for the development of a productive and sustainable agriculture, and is mainly oriented ...
Rodino A.P. +4 more
doaj
Analysis of observations indicates that there was a rapid increase in summer (June–August) mean surface air temperature (SAT) since the mid-1990s over Western Europe.
B. Dong, R. Sutton, L. Shaffrey
semanticscholar +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Forests and the national greenhouse gas inventory of Germany. COST E21 Workshop. Contribution of forests and forestry to mitigate greenhouse effects. Joensuu (Finland). 28-30 Sep 2000 [PDF]
Since 1995, experiences have been gathered with the calculation of National Greenhouse Gas Inventories in Germany. Because only marginal changes of the total forested area occur in Germany, relevant changes of the balance of greenhouse gases in the ...
Baritz R., Strich S.
doaj
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
The use of the soil map of Belgium in the assessment of landslide risk [PDF]
The analysis is based on a report from the Laboratory of Geomorphology and Remote sensing of the University of Liege concerning Mont-de-l'Enclus hill (Province of Hainaut, 20 kilometers north of the city of Tournai).
Closson D., Engels P., Demaret X.
doaj
A Comparative Analysis of Initiatives and Adaptation Measures to Climate Change Undertaken in Poland and Western Europe [PDF]
The analysis of the main initiatives for adaptation to climate change in selected countries of Western Europe and Poland relate to key issues mentioned in the strategic documents of the European Commission.
Michalak, Dorota
core +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Contribution of forests and forestry in Finland to mitigate greenhouse effect. COST E21 Workshop. Contribution of forests and forestry to mitigate greenhouse effects. Joensuu (Finland). 28-30 Sep 2000 [PDF]
Ministry of the Environment is coordinating matters related to the unitéd Nation Framework Convention on Climate Change. National reporting of greenhouse gas inventories for land-use change and forestry category utilises forest inventory results with ...
Karjalainen,T., Maekipaeae R.
doaj

