Results 61 to 70 of about 641,559 (279)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Extreme right-wing voting in Western Europe [PDF]

, 2002
In this study we explain extreme right-wing voting behaviour in the countries of the European Union and Norway from a micro and macro perspective. Using a multidisciplinary multilevel approach, we take into account individual-level social background ...
Adorno, Andersen, Anderson, Anker, Arendt, Baimbridge, Baimbridge, Beerten, Betz, Betz, Beyme, Billiet, Blalock, Brug, Centre d'Études de la Vie Politique Francaise (CEVIPOF), Centre d'Études de la Vie Politique Francaise (CEVIPOF), CRAPS, Le CIDSP et Libération, Coenders, Davis, Dooren, Downs, Durkheim, Eatwell, Erikson, European Commission, Falter, Falter, Fromm, Ganzeboom, Holmberg, Huber, Husbands, Husbands, Husbands, Ignazi, Jackman, Kitschelt, Knigge, Kornhauser, Lindholm, Lipset, Lubbers, Lubbers, Lubbers, Lubbers, Mayer, Mayer, Mayer, Melich, Minkenberg, Mudde, Olzak, Quillian, Rasbash, Scheepers, Scheepers, Schmitt, Snijders, Tajfel, Tajfel, Thraenhardt, United Nations, Wal, Winkler, Witte, Zentralarchiv für Empirische Sozialforschung   +64 more
core   +3 more sources

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Inflation in Western Europe and Japan [PDF]

Inflation (Finance) - Western Europe ; Inflation (Finance ...
anonymous
core  

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro, María Victoria Zelaya, Hasier Eraña, Javier Sánchez Ruiz de Gordoa, Fermín García‐Amigot, Anika Simonovska‐Serra, María Cristina Caballero, Isidre Ferrer, Ellen Gelpi, Ivonne Jericó, Joaquín Castilla   +10 more
wiley   +1 more source

Epidemiology of taeniosis/cysticercosis in Europe, a systematic review: Western Europe

Parasites & Vectors, 2017
Background Taenia solium and Taenia saginata are zoonotic parasites of public health importance. Data on their occurrence in humans and animals in western Europe are incomplete and fragmented.
Minerva Laranjo-González, Brecht Devleesschauwer, Chiara Trevisan, Alberto Allepuz, Smaragda Sotiraki, Annette Abraham, Mariana Boaventura Afonso, Joachim Blocher, Luís Cardoso, José Manuel Correia da Costa, Pierre Dorny, Sarah Gabriël, Jacinto Gomes, María Ángeles Gómez-Morales, Pikka Jokelainen, Miriam Kaminski, Brane Krt, Pascal Magnussen, Lucy J. Robertson, Veronika Schmidt, Erich Schmutzhard, G. Suzanne A. Smit, Barbara Šoba, Christen Rune Stensvold, Jože Starič, Karin Troell, Aleksandra Vergles Rataj, Madalena Vieira-Pinto, Manuela Vilhena, Nicola Ann Wardrop, Andrea S. Winkler, Veronique Dermauw   +31 more
doaj   +1 more source

Diagnostic Utility of the ATG9A Ratio in AP‐4–Associated Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adaptor protein complex 4–associated hereditary spastic paraplegia (AP‐4‐HSP), a childhood‐onset neurogenetic disorder and frequent mimic of cerebral palsy, is caused by biallelic variants in the adaptor protein complex 4 (AP‐4) subunit genes (AP4B1 [for SPG47], AP4M1 [for SPG50], AP4E1 [for SPG51], and AP4S1 [for SPG52]).
Habibah A. P. Agianda, Hyo‐Min Kim, Nicole Battaglia, Joshua Rong, Amy Tam, Enrique Gonzalez Saez‐Diez, Cornelius F. Boerkoel, Afshin Saffari, Vicente Quiroz, Luca Schierbaum, Zainab Zaman, Katerina Bernardi, Darius Ebrahimi‐Fakhari   +12 more
wiley   +1 more source

Demographic Diversity and Convergence in Europe, 1918-1990

Demographic Research, 2002
The study investigates how Hungarian demographic development from the end of World War I to 1990 related to the changes that took place in Western Europe, and in which areas and in what periods can divergence or convergence be observed.
doaj  

Minority Muslim Communities in Post-Bipolar Europe (Western Europe & the Balkans)

American Journal of Islam and Society, 1995
A conference on Minority Muslim Communities in Post-Bipolar Europe (Western Europe & the Balkans), convened by the Centre for Middle Eastern and Islamic Studies at the University of Durham (UK), was held at the Regency Palace Hotel in Amman at the ...
Suha Taji-Farouki
doaj   +1 more source

Western Europe

Global Heart, 2014
Hugh Clout, Mark Blacksell, Russell King, David Pinder   +3 more
  +6 more sources