Results 41 to 50 of about 26,440 (305)

A new king in the Western Desert

, 2023
One of the early royal names documented by Winkler in the Western Desert has, until now, escaped the attention of Egyptologists. Taking into account current knowledge of early royal epigraphy and of late Predynastic political developments, a date is ...
Toby Wilkinson (17170018)
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Art of the Western Desert [PDF]

, 1978
Art of the Western Desert Fine Arts Gallery, University Centre 4-23 September 1978.
Djuburula, JW, Djabaldjari, BS, Djagamara, A, Djabaldjari, TL, Djuburula, NT, Djambidjimba, KM, Djagamara, FW, Djungarai, CT, Djuburula, TT, Djabaldjari, CE, Djagamara, MW, Djagamara, JP, Djungarai, SL   +12 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Some normal hematological values of Arabian camels reared in western desert of Al-Najaf governorate/ Iraq [PDF]

Mirror of Research in Veterinary Sciences and Animals, 2015
This study was designed to study some normal hematological values of Arabian camels reared in western desert of Al-Najaf governorate/ Iraq. Blood samples was collected with anticoagulant tube from 78 free breeding Arabian camels in western desert of Al ...
Hayder M. Al-Rammahi, Hamed A. Al-Jebory, Huda Abed Al-Sattar   +2 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Evaluation of the nature, origin and potentiality of the subsurface Middle Jurassic and Lower Cretaceous source rocks in Melleiha G-1x well, North Western Desert, Egypt

Egyptian Journal of Petroleum, 2015
The present work aims to evaluate the nature and origin of the source rock potentiality of subsurface Middle Jurassic and Lower Cretaceous source rocks in Melleiha G-1x well.
Mohamed M. El Nady
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Analyse et typologie des «représentations féminines» préhistoriques dans l’art rupestre de la région de Chufu, Désert occidental égyptien

Afrique Archéologie Arts, 2023
Many geological, environmental, and archaeological pieces of evidence in the Egyptian Western Desert point to the important role that the desert played in the cultural development along the Nile, especially during the Late Prehistoric Period. The process
Nourhan Moustafa
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source