Results 51 to 60 of about 24,556 (268)

Variabilidad de la frecuencia cardiaca en pacientes con cardiopatía chagásica

Revista U.D.C.A Actualidad & Divulgación Científica, 2020
Se estima la prevalencia por Trypanosoma cruzi de 436.000 habitantes en Colombia, con casos anuales de 5.250, en población expuesta de 4.792.000 habitantes.
Jose Ricardo Corredor-Matus, Fernando Riveros-Sanabria, Laura Tatiana Corredor-Mesa   +2 more
doaj   +1 more source

BIOLOGICAL ASPECTS AND PHYTOCHEMISTRY OF THREE DESERT PLANTS GROWING IN WESTERN DESERT, EGYPT. [PDF]

Journal of Plant Production, 2015
The present study aims to investigate morphology, and anatomy of Astragalus vogelii, Bassia muricata and Morettia philaeana growing in Abu Tartur region, that lies between Kharga and Dakhla Oases in Western Desert of Egypt. Polyphenols, flavonoids, fatty
M. Jalal, M. Al-Shami, M. Abu Ziada
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

The Paradox of Kellis (Western Egyptian Desert)

The Journal of Greco-Roman Studies, 2019
Kellis is a small village in the Dakhlah Oasis in the Western Egyptian desert. From the perspective of spatiality, Kellis seems to epitomise isolation and remoteness, whereas from the perspective of language usage, Kellis seems to exemplify integration and mixture.The article aims to explain this paradox.
openaire   +2 more sources

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Etiology, Biological Characteristics, and Fungicide Sensitivity of Bipolaris sorokiniana Causing Root Rot in Wild Orchardgrass (Dactylis glomerata L.)

Agronomy
Dactylis glomerata is a globally important cool-season forage grass with high ecological and economic value. During field surveys conducted in three counties of the Ili region of Xinjiang, Zhaosu County, Tekes County, and Xinyuan County, a previously ...
Lei Shan, Zhenyu Yang, Sen Sun, Benzhong Fu, Lili Wang   +4 more
doaj   +1 more source

Desert tourism development in Egypt by application on the Western desert

Journal of Association of Arab Universities for Tourism and Hospitality, 2007
The Egyptian Sahara Is part of the Great Sahara desert of northern Africa, with an estimated area of about one million, two hundred Sq Km. The Nile Valley divides it to WesternDesert and EasternDesert. The NileValley is considered a river oasis covering about 4% of the area of Egypt where there is a high density of the population, agricultural and ...
openaire   +1 more source