Results 51 to 60 of about 2,391,044 (330)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Some normal hematological values of Arabian camels reared in western desert of Al-Najaf governorate/ Iraq [PDF]
Mirror of Research in Veterinary Sciences and Animals, 2015 This study was designed to study some normal hematological values of Arabian camels reared in western desert of Al-Najaf governorate/ Iraq. Blood samples was collected with anticoagulant tube from 78 free breeding Arabian camels in western desert of Al ...
Hayder M. Al-Rammahi +2 more
doaj
International Soil and Water Conservation Research, 2018 People living in arid and semi-arid areas with highly variable rainfall and unforeseeable periods of droughts or floods are severely affected by water shortages and often have insecure livelihoods.
Ammar Adham +8 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Egyptian Journal of Petroleum, 2015 The present work aims to evaluate the nature and origin of the source rock potentiality of subsurface Middle Jurassic and Lower Cretaceous source rocks in Melleiha G-1x well.
Mohamed M. El Nady
doaj +1 more source
Afrique Archéologie Arts, 2023 Many geological, environmental, and archaeological pieces of evidence in the Egyptian Western Desert point to the important role that the desert played in the cultural development along the Nile, especially during the Late Prehistoric Period. The process
Nourhan Moustafa
doaj +1 more source
Review of Flying to Victory: Raymond Collishaw and the Western Desert Campaign, 1940-1941 by Mike Bechthold [PDF]
, 2019 Review of Flying to Victory: Raymond Collishaw and the Western Desert Campaign, 1940-1941 by Mike ...
Stubbs, David
core +1 more source
, 1988 Number of Pages: 3Integrative BiologyGeological ...
Dickson, Nancy A., Vitt, Laurie J.
core +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source