Results 191 to 200 of about 4,039,961 (280)

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

Advanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung, Xu Wang, Bin Liu, Raktim Roy, Nancy Jaiswal, Ratan K. Rai, Yuichiro Takagi, Cen Gao, Lifan Zeng, Ho‐Yin Lo, Reagan K. Wohlford, Ryan K. Higgins, Bruce T. Lamb, Anantha Shekhar, Anita C. Bellail, Chunhai Hao   +15 more
wiley   +1 more source

Aedes albopictus Is Rapidly Invading Its Climatic Niche in France: Wider Implications for Biting Nuisance and Arbovirus Control in Western Europe. [PDF]

Glob Chang Biol
Radici A, Hammami P, Cannet A, L'Ambert G, Lacour G, Fournet F, Garros C, Guis H, Fontenille D, Caminade C.   +9 more
europepmc   +1 more source

Western Europe

, 2006
Kenneth E. Corey, Mark Wilson
openaire   +1 more source

An Unbiased Geometry‐Resolved Membrane Platform for Proteome‐Scale Discovery of Membrane Curvature Sensors

Advanced Science, EarlyView.
A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa, Rikuto Kawakami, Kunanon Chattrairat, Tatsuya Niwa, Taiga Ajiri, Takao Yasui, Masayoshi Tanaka   +6 more
wiley   +1 more source

Genetic structure and demographic history of house mice in western Europe inferred using whole-genome sequences. [PDF]

Proc Biol Sci
Agwamba K, Smith L, Gabriel SI, Searle JB, Nachman MW.   +4 more
europepmc   +1 more source

Effects of Environmental and Health Information on Willingness to Pay for Local and Organic Foods in Taiwan

Agribusiness, EarlyView.
ABSTRACT Using a lab‐in‐the‐field experiment, we investigate how providing information about food miles and pesticide residue influences willingness to pay (WTP) for potatoes among 407 shoppers in Taiwan, split between a supermarket and a farmers market.
Chiu‐Lin Huang, Edward C. Jaenicke, Martina Vecchi, Sheng‐Jang Sheu   +3 more
wiley   +1 more source

Identifying the richness and evolutionary relationships of Ranunculus sect. Batrachium in its diversity centre in south-western Europe. [PDF]

Sci Rep
Prančl J, Koutecký P, Lučanová M, Nagy Nejedlá M, Brožová V, Dolejšek V, Košnar J, Trávníček P, Kaplan Z.   +8 more
europepmc   +1 more source

Who Are the Consumers of European Farmers' Markets? A Cross‐Country Analysis

Agribusiness, EarlyView.
ABSTRACT With substantial growth in the number of farmers' markets (FMs) in developed countries, the number of consumers visiting FMs is also increasing. This study comparatively assesses the consumers of FMs in three European countries where FMs traditionally play a distinctive role in food supply chains.
Áron Török, Gréta Maró, Zsófia Jámbor, Zalán Márk Maró, Barbara Tocco, Péter Balogh, Péter Czine   +6 more
wiley   +1 more source

Avoidable mortality does not allow valid conclusions on population health and health system quality in Western Europe. [PDF]

Lancet Reg Health Eur
Stolpe S, Kowall B.
europepmc   +1 more source

Regional Differences in U.S. Consumer Preferences for Native Woody Shrubs With Varying Aesthetic Characteristics

Agribusiness, EarlyView.
ABSTRACT Native plants offer a variety of aesthetic (e.g., fall colour, fruit, flowers) and functional benefits (e.g., pollinator friendly, wildlife friendly, water management). How these benefits influence consumer choice and perceived value of native versus introduced plants is not well understood.
Alicia Rihn, Ariana P. Torres, Sue Barton, Bridget K. Behe   +3 more
wiley   +1 more source