Results 171 to 180 of about 4,039,961 (280)

Prevalence and Incidence of Dilated Cardiomyopathy in the United States and Western Europe: A Systematic Review. [PDF]

Cardiol Res
Myers MC, Berge A, Zhong Y, Maruyama S, Bueno C, Bastien A, Hofer K, Kaur R, Fazeli MS, Golchin N.   +9 more
europepmc   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

The New and Old Europe: East-West Split in Pharmaceutical Spending

Frontiers in Pharmacology, 2016
Mihajlo (Michael) Jakovljevic, Marija eLazarevic, Olivera eMilovanovic, Tatjana eKanjevac   +3 more
doaj   +1 more source

Trends in myopia prevalence and projected visual impairment in Western Europe: a pooled analysis of Dutch population-based cohorts (1900-2000). [PDF]

BMJ Public Health
Kneepkens S, Enthoven CA, Polling JR, de Vries VA, Tideman JWL, Klaver C, Eye Epidemiology research group.   +6 more
europepmc   +1 more source

OsCPK12‐OsATPD1 Module Regulates Photosynthetic Acclimation to Light Stress in Rice

Advanced Science, EarlyView.
OsCPK12 interacts and phosphorylates OsAtpD1 at Ser8 in its transit peptide. This phosphorylation promote its chloroplast translocation, thereby maintaining ATP synthase activity and proton gradient (ΔpH) homeostasis and regulating photosynthetic acclimation, photoprotection, and repair under light stress.
Beifang Wang, Aaron Chan, Yongyi Fan, Yanwu Wang, Pao Xue, Yingxin Zhang, Xiaodeng Zhan, Weixun Wu, Ping Yu, Daibo Chen, Junlin Fu, Yongbo Hong, Xihong Shen, Lianping Sun, Aike Zhu, Shihua Cheng, Qunen Liu, Liyong Cao   +17 more
wiley   +1 more source

Tabes dorsalis: a rare presentation of neurosyphilis in Western Europe. [PDF]

BMJ Case Rep
Bloch N, Brugger F, Notter J.
europepmc   +1 more source

Inorganic Nanomaterials can Promote or Inhibit Tumor Metastasis Depending on Tumor Microenvironment Composition

Advanced Science, EarlyView.
As engineered nanomaterials gain prominence in cancer imaging and therapy, understanding their impact on tumor progression becomes increasingly critical. We demonstrate that gold and silica‐coated gold nanomaterials can either suppress or enhance breast cancer metastasis through distinct tumor microenvironment interactions, while identifying ...
Kiana Buttiens, Xiaoqi Zheng, Xueqi Fan, Mukaddes Izci, Christy Maksoudian, Irati Perez Gilabert, Tianjiao Chu, Filipa Goncalves, Jonas Dehairs, Johan Swinnen, Bella B. Manshian, Stefaan J. Soenen   +11 more
wiley   +1 more source

Climate Change Does Not Directly Influence Red Squirrel ( <i>Sciurus vulgaris</i> ) Distribution in Western Europe. [PDF]

MicroPubl Biol
Buchanan AEV, Gillingham PK, Andreou D, Hodder KH, Toups MA, Butler H, Hardouin EA.   +6 more
europepmc   +1 more source

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial‐Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C‐Dependent Stabilization of Snail mRNA

Advanced Science, EarlyView.
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao, Linlin Yang, Huanxiang Chen, Chenfeng Guo, Hongshen Lu, Ying Zhu, Xuanzhi Wang, Yang Li, Ruike Zhang, Zichong Huang, Yifang Chen, Keyu Jin, Zeduo Xu, Lingxiu Meng, Longfeng Zhang, Yuanyuan Han, Yicong Yan, Qiaozhen Kang, Junhu Wan, Hongyang Liu   +19 more
wiley   +1 more source

Developing an Adult Living Donor Liver Transplant Program in Western Europe: The Rotterdam Experience. [PDF]

Transpl Int
Chorley AJ, Polak WG, Tran KCK, Terkivatan T, Kissler J, Doukas M, Den Hoed C, Thomeer MG, Dwarkasing R, Metselaar H, Ijzermans JNM, Porte RJ, Kuipers EJ, Minnee RC, Boehnert M.   +14 more
europepmc   +1 more source