Results 151 to 160 of about 258,169 (218)

Prevalence and Incidence of Dilated Cardiomyopathy in the United States and Western Europe: A Systematic Review. [PDF]

Cardiol Res
Myers MC, Berge A, Zhong Y, Maruyama S, Bueno C, Bastien A, Hofer K, Kaur R, Fazeli MS, Golchin N.   +9 more
europepmc   +1 more source

GSLR Drives Lung Adenocarcinoma as a Critical Regulator of Energy Homeostasis Through Creatine Kinase B Activation

Advanced Science, EarlyView.
This study identifies the glucose/glutamine sensitive lncRNA GSLR as a driver of lung adenocarcinoma progression. Nutrient restriction reduces chromatin accessibility at the GSLR locus and blocks CTCF‐mediated transcriptional regulation. GSLR directly interacts with DHX9 and recruits it to the CKB promoter, arresting R‐loop accumulation and promoting ...
Xinyi Qian, Juze Yang, Jiayi Ren, Xiaowei Mao, Jia Li, Tengfei Sun, Liangliang Dong, Enguo Chen, Yan Lu, Pengyuan Liu   +9 more
wiley   +1 more source

The New and Old Europe: East-West Split in Pharmaceutical Spending

Frontiers in Pharmacology, 2016
Mihajlo (Michael) Jakovljevic, Marija eLazarevic, Olivera eMilovanovic, Tatjana eKanjevac   +3 more
doaj   +1 more source

Trends in myopia prevalence and projected visual impairment in Western Europe: a pooled analysis of Dutch population-based cohorts (1900-2000). [PDF]

BMJ Public Health
Kneepkens S, Enthoven CA, Polling JR, de Vries VA, Tideman JWL, Klaver C, Eye Epidemiology research group.   +6 more
europepmc   +1 more source

Stimulation of OGG1 Enhances Oxidative DNA Damage Repair and Protects Against Acute Liver Failure by Acetaminophen

Advanced Science, EarlyView.
Chemical switching of OGG1 by CMM‐98 accelerates oxidative DNA damage repair and enhances hepatocyte resilience during acetaminophen‐induced acute liver injury. By promoting efficient processing of OGG1‐generated repair intermediates, CMM‐98 reduces oxidative damage, preserves cellular integrity, and protects against acute liver failure, identifying ...
Zhenjun Zhao, Rahul Upadhyay, Alice Eddershaw, Chenchen Wang, Yudong Zhao, Olov Wallner, Jinhye Ryu, Nayere Taebnia, Heather Gildie, Emma Scaletti‐Hutchinson, Jonathan R. Davies, Nicole Ziegler, Andreas Krämer, Samantha C. Robinson, Marek Varga, Karolina Singerova, Zuzanna Szaruga, Elisée Wiita, İrşil Güneş, Sheila S. David, Stefan Knapp, Aimo Kannt, Miguel de Vega, Pål Stenmark, Volker M Lauschke, Maurice Michel   +25 more
wiley   +1 more source

Climate Change Does Not Directly Influence Red Squirrel ( <i>Sciurus vulgaris</i> ) Distribution in Western Europe. [PDF]

MicroPubl Biol
Buchanan AEV, Gillingham PK, Andreou D, Hodder KH, Toups MA, Butler H, Hardouin EA.   +6 more
europepmc   +1 more source

Extracellular Vesicle Packaged TDP43 Derived From ECs Exacerbates Cigarette Tar‐Related Atherosclerosis Progression via Enhancing Macrophage Extracellular Traps

Advanced Science, EarlyView.
Cigarette tar triggers EC‐derived EVs carrying TDP43, which binds VDAC1 to boost MAMs, mitochondrial Ca2+ overload, and METs formation in macrophages, accelerating smoking‐related AS progression, while retinoic acid binds TDP43 to block this pathogenic cascade.
Xinxin Zhu, Yuwu Chen, Wei Meng, Biyi Xu, Junke Mou, Xiaolin Liu, Mengyang Wang, Qishuo Gu, Qianhui Sun, Man Li, Chen Zhao, Ming Zeng, Ying Lv, Boling Yi, Sheng Qu, Xiaoxuan Bai, Ji Li, Xing Luo, Sining Hu, Bo Yu, Haibo Jia   +20 more
wiley   +1 more source

Developing an Adult Living Donor Liver Transplant Program in Western Europe: The Rotterdam Experience. [PDF]

Transpl Int
Chorley AJ, Polak WG, Tran KCK, Terkivatan T, Kissler J, Doukas M, Den Hoed C, Thomeer MG, Dwarkasing R, Metselaar H, Ijzermans JNM, Porte RJ, Kuipers EJ, Minnee RC, Boehnert M.   +14 more
europepmc   +1 more source

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source

Correction: Extent and diversity of recognized Indigenous and community lands: Cases from Northern and Western Europe. [PDF]

Ambio
Bebbington A, Shrestha Sangat S, Golden Kroner RE, Mustonen T.   +3 more
europepmc   +1 more source