Results 131 to 140 of about 351,727 (307)
Advanced Science, EarlyView.Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia +17 more
wiley +1 more source
Integrating multimorbidity education into undergraduate medical curriculum: A systematic review
Future Healthcare JournalMultimorbidity is becoming highly prevalent across the globe. Current medical curricula predominantly focus on single-disease management, leaving future physicians underprepared to provide patient-centred care to address the multimorbidity epidemic ...
Andrea Cuschieri +2 more
doaj +1 more source
Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties
Advanced Science, EarlyView.Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez +16 more
wiley +1 more source
Diasporic Greek-Australian writing deconstructed : challenging Europe with new voices, new perspectives [PDF]
, 2007 This paper will concentrate on a particular methodology which aims to deconstruct the literature of diasporic Greek Australian writers, mainly that written by Christos Tsiolkas and Vasso Kalamaras, and compare this with particular themes explored by the ...
Dimitriou, Anna (R20328)
core
CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation
Advanced Science, EarlyView.ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu +10 more
wiley +1 more source
A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation
Advanced Science, EarlyView.A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu +7 more
wiley +1 more source
Migration, labor markets, and integration of migrants: An overview for Europe [PDF]
This paper discusses the size of Europe's migrant population, its demographic structure, and the socio-economic position of migrants. The European Labour Force Survey (LFS) as well as Eurostat, OECD and UN migration data are used as the main databases ...
Münz, Rainer
core
UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation
Advanced Science, EarlyView.ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro +7 more
wiley +1 more source
PRIVATE SECTOR AGRICULTURAL TENANCY ARRANGEMENTS IN EUROPE: THEMES AND DIMENSIONS; A CRITICAL REVIEW OF CURRENT LITERATURE [PDF]
Although there is widespread support for the "ideal model" of agricultural production being based around the owner-occupier farmer, it is recognized that, for a variety of reasons, this ideal is neither always attainable nor desirable.
Markwell, Susan +2 more
core +1 more source