Results 211 to 220 of about 1,861,889 (296)

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li, Jie Yuan, Min Gao, Jibin Liu, Qinqin Wang, Yaqi Zhang, Mingtao Cao, Xiaolin Hu, Hui Yang, Jun Li, Chen Li, Xiaoguang Li, Hui Wang   +12 more
wiley   +1 more source

Tabes dorsalis: a rare presentation of neurosyphilis in Western Europe. [PDF]

BMJ Case Rep
Bloch N, Brugger F, Notter J.
europepmc   +1 more source

Microcystin‐LR Triggers Renal Tubular Ferroptosis Through Epigenetic Repression of GPX4: Implications for Environmental Nephrotoxicity

Advanced Science, EarlyView.
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang, Qi Gao, Yi Peng, Huan Zhang, Qi Shen, Meihong Guo, Yuqing Gong, Lei Chu, Weidong Wu, Yanting Wen, Wangsen Cao, Yong Wang, Lihui Wang   +12 more
wiley   +1 more source

Developing an Adult Living Donor Liver Transplant Program in Western Europe: The Rotterdam Experience. [PDF]

Transpl Int
Chorley AJ, Polak WG, Tran KCK, Terkivatan T, Kissler J, Doukas M, Den Hoed C, Thomeer MG, Dwarkasing R, Metselaar H, Ijzermans JNM, Porte RJ, Kuipers EJ, Minnee RC, Boehnert M.   +14 more
europepmc   +1 more source

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

Advanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló, Elisabetta Ada Cavalcanti‐Adam, Carlos Mas‐Moruno   +2 more
wiley   +1 more source

Correction: Extent and diversity of recognized Indigenous and community lands: Cases from Northern and Western Europe. [PDF]

Ambio
Bebbington A, Shrestha Sangat S, Golden Kroner RE, Mustonen T.   +3 more
europepmc   +1 more source

Between secularization and migration: religiosity of minority youth in Western Europe [PDF]

, 2020
Konstanze Jacob
openalex  

A higher‐level classification of the Pannonian and western Pontic steppe grasslands (Central and Eastern Europe) [PDF]

, 2016
Wolfgang Willner, Анна Куземко, Jürgen Dengler, Milan Chytrý, Norbert Bauer, Thomas Becker, Claudia Biţǎ‐Nicolae, Zoltán Botta‐Dukát, Andraž Čarni, János Csiky, Ružica Igić, Zygmunt Kącki, Iryna Korotchenko, Matthias Kropf, Mirjana Krstivojević‐Ćuk, Daniel Krstonošić, Tamás Rédei, Eszter Ruprecht, Luise Schratt‐Ehrendorfer, Yuri Semenishchenkov, Zvjezdana Stančić, Yulia Vashenyak, Denys Vynokurov, Monika Janišová   +23 more
openalex   +1 more source

Banking in Western Europe. [PDF]

Kleimeier, Stefanie
core   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source