Results 61 to 70 of about 1,861,889 (296)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Stany Zjednoczone a integracja polityczna, militarna i gospodarcza Europy Zachodniej w pierwszych latach po II wojnie światowej (do 1950 r.). Ameryka nadaje ton i dyktuje warunki (Część I)

open access: yesHistoria i Polityka, 2019
The influence of the US on the forms and course of the integration processes in Western Europe was very strong, especially in the first post-war years.
Zbigniew Klimiuk
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Bilatéralité vs conceptions androcentriques de la parenté en Europe : quelques réflexions à partir des arbores consanguinitatis de la fin du Moyen Âge

open access: yesGenre & Histoire, 2018
The article examines some ways in which scholars of the late Middle Ages used canon law conceptualizations of kinship to visualize and understand kinship more broadly. A particular focus is on the diagram of the arbor consanguinitatis.
Simon Teuscher
doaj   +1 more source

Demographic Diversity and Convergence in Europe, 1918-1990

open access: yesDemographic Research, 2002
The study investigates how Hungarian demographic development from the end of World War I to 1990 related to the changes that took place in Western Europe, and in which areas and in what periods can divergence or convergence be observed.
doaj  

Muslim сommunities in the USA and Western Europe: patterns of electoral behavior

open access: yesНаучно-аналитический вестник Института Европы РАН
The year 2024 will see electoral events of particular importance: not only will they, like those that preceded them, determine the direction of development of socio-political life in the United States and Western Europe for at least the next four years ...
Inna V. Shumilina
doaj   +1 more source

On the Measurement of the Income Poverty Rate: the Equivalence Scale across Europe [PDF]

open access: yesStatistika: Statistics and Economy Journal, 2019
The methodology used to determine the at-risk-of-poverty rate commonly applied in the European context is often criticised for arbitrary steps in its construction.
Martina Mysíková, Tomáš Želinský
doaj  

The Formation of Civil Society and Party-Political system: the Experience of India

open access: yesКонтуры глобальных трансформаций: политика, экономика, право, 2018
The article, India taken as a case study, is focused on civil  society/party system interrelationship. Among origins of comparative  advancement of India’s party system are such  historical constituents as: lasting existence of “centre- periphery ...
A. G. VOLODIN
doaj   +1 more source

Who Needs Credit and Who Gets Credit in Eastern Europe? [PDF]

open access: yes
Based on survey data covering 8,387 firms in 20 countries we compare credit demand and credit supply for firms in Eastern Europe to those for firms in selected Western European countries.
Alexander Popov   +3 more
core  

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