Results 61 to 70 of about 351,727 (307)

Local Governance in Western Europe [PDF]

, 2001
Book synopsis: `Its strength lies in combining theoretical insights with an impressive range of empirical material. The analysis is subtle and multi-layered....
John, P C., John, Peter
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

ANALYSIS OF THE RELATIONSHIP BETWEEN INNOVATION AND PERFORMANCE. THE CASE OF ROMANIA VERSUS THE COUNTRIES OF WESTERN EUROPE [PDF]

Annals of the University of Craiova: Economic Sciences Series, 2020
The research paper consists in analyzing the relationship between investments in innovation and macroeconomic performance indicators. Recent scientific literature argues that investment in innovation has a direct and positive impact on the performance of
Alin-Ionuț Dorobanțu
doaj  

In the Name of Sovereignty. Right-Wing Populism and the Power of the Judiciary in Western Europe

Partecipazione e Conflitto, 2020
This contribution addresses the question of how radical right-wing populist parties in Western Europe frame the issue of judicial power. To date, there have been very few in-depth empirical analyses on the topic – a gap that this article aims to fill ...
Oscar Mazzoleni, Gerrit Voerman
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Efta-barometer autumn 1992: Austria, Finland and Sweden [PDF]

, 1993
The survey was carried out simultaneously in the three EFTA-countries Austria, Finland, and Sweden. In each country approximately 1 000 persons were asked about their opinions about a unified Western Europe, and personal interest in European Community ...
Gallup Europe
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Economic Stances of Ultranationalist Parties in Western Europe

methaodos.revista de ciencias sociales
The increasing electoral successes of ultranationalist parties in Western Europe have generated an immense number of terms to describe them with radical right, extreme right and populism being the most common denominations.
Javier Matamoros-Becerra
doaj   +1 more source

Stany Zjednoczone a integracja polityczna, militarna i gospodarcza Europy Zachodniej w pierwszych latach po II wojnie światowej (do 1950 r.). Ameryka nadaje ton i dyktuje warunki (Część I)

Historia i Polityka, 2019
The influence of the US on the forms and course of the integration processes in Western Europe was very strong, especially in the first post-war years.
Zbigniew Klimiuk
doaj   +1 more source