Results 31 to 40 of about 72,221 (254)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
AICEI Proceedings, 2018 The economies and political systems of most European countries have successfully integrated to the European Union while also maintaining their sovereignty.
Bettina Jones +2 more
doaj +1 more source
Studia Europejskie, 2023 Although Western Balkan economies are still on the list of EU candidates or potential candidate countries, they do have some integration with EU economies.
Tomasz Grodzicki
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
STED JournalThis paper aims to explore the structure and objectives of the Western Balkans Growth Plan as an incentive for the integration of the Western Balkans region into the EU single market. In november 2023, the European Commission prepared the Western
Manja Đurić Džakić
doaj +1 more source
The Rise of Right-Wing Extremism in European Union
International Studies: Interdisciplinary Political and Cultural Journal, 2015 It is a fact that in the European Union there is a strengthening of right-wing extremism, radical right movement, populism and nationalism. The consequences of the economic crisis, such as a decline in living standards, losing of jobs, rising ...
Ljupcho Stevkovski
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
INFLUENCE OF NON-WESTERN ACTORS IN THE BALKANS [PDF]
EURINT, 2021 In recent years, the balance of power of international actors has changed significantly. The emergence of non-Western powers on the global and especially regional stage is reducing the Western domination in the Balkans.
Roland LAMI, Blendi LAMI
doaj
CURRENT SECURITY CHALLENGES IN THE WESTERN BALKANS AND CONSEQUENCES OF THE WAR IN UKRAINE
Bezbednosni Dijalozi, 2023 The Russian invasion of Ukraine, which began at the end of February 2022, confirmed the de facto impotence of the EU policy towards the Western Balkans. Only the reaffirmation of the United States of America and NATO’s roles in the Western Balkans after ...
Dragan Đukanović
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source