Results 131 to 140 of about 626,286 (260)

A Dual‐Delivery System Designed to Overcome EV‐Mediated Ferroptosis Resistance for Efficient Solid Tumor Therapy

Advanced Science, EarlyView.
(A) Establishment and characterization of the osteosarcoma‐targeted dual‐delivery nanoplatform mBAP1/siENO1@LNP‐OTP for simultaneous regulation of BAP1 and ENO1 in tumor cells. (B) After intravenous administration, mBAP1/siENO1@LNP‐OTP preferentially accumulates at tumor sites through OTP‐mediated targeting.
Yechao Shen, Zhenguo Cao, Zenan Wang, Liang Chen, Jiahao Zhang, Linjie Zeng, Boren Tan, Hengyuan Li, Jiashan Lai, Jiangchu Lei, Fanglu Chen, Peng Lin, Zhenxuan Shao, Zhan Wang   +13 more
wiley   +1 more source

Aged ZnO Nanoparticles Promote Breast Cancer Lung Metastasis by Remodeling the Pulmonary Microenvironment Through the CXCL10/Wnt/β‐Catenin Axis

Advanced Science, EarlyView.
In summary, pulmonary exposure to ZnO NPs, particularly aged NPs, promotes breast cancer metastasis by remodelling the lung tumour microenvironment. Aged ZnO NPs enrich M2‐macrophages, MDSCs and activated CAFs to form an immunosuppressive metastatic niche. CXCL10 from these cells drives metastasis via Wnt/β‐catenin activation.
Yong Zhu, Siyu Wang, Tong Lin, Jingyi Zhang, Jingya Yang, Dixiang Kang, Wenting Zhao, Na Yu, Meimei Wang   +8 more
wiley   +1 more source

Abstracts presented at the Western Society of Allergy, Asthma & Immunology, February 1-5, 2026, Wailea, Hawaii. [PDF]

Allergy Asthma Proc
europepmc   +1 more source

Improved Skills for Predicting Sub‐Seasonal to Seasonal Global Sea Surface Temperature

Advanced Science, EarlyView.
Addressing the critical Sub‐seasonal to Seasonal predictability gap, this study presents CAS‐Canglong, a novel deep learning framework. By leveraging 3D Swin‐Transformers to capture long‐range ocean interactions, the model demonstrates superior skill over traditional GCMs.
Longhao Wang, Xuanze Zhang, Ruby L. Leung, Francis H. S. Chiew, Amir AghaKouchak, Kairan Ying, Yongqiang Zhang   +6 more
wiley   +1 more source

Enzyme‐Linked Cycloaddition Assay (ELCA) for Rapid, Ultra‐Sensitive Monitoring of Secreted Sialoglycoproteins

Advanced Science, EarlyView.
Secreted glycoproteins report on cellular state faster than the cell surface, yet remain hard to measure. The Enzyme‐Linked Cycloaddition Assay (ELCA) combines metabolic azide labeling with click chemistry in an ELISA‐like microplate format, resolving sialylation changes within minutes for 1‐2 EUR per sample.
Jon Lundstrøm, Jingmei Yang, Daniel Bojar   +2 more
wiley   +1 more source

Complementary or Competitive? Emerging Interactions Between Restoration and Protection in the Conservation Reserve Program

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT The USDA's Conservation Reserve Program (CRP) delivers environmental benefits to society by enrolling cropland and grasslands to reestablish or safeguard long‐term vegetative cover. In recent years, the CRP has dramatically increased grassland enrollment while cropland enrollment has been in steady decline. This paper uses descriptive analysis,
Wesley Zebrowski, Tyler Lark, Rich Iovanna   +2 more
wiley   +1 more source

Urban Indigenous Communities Transforming Health Care: "Where We Feel Safe and Where Our People Are Working". [PDF]

AlterNative (Nga Pae Maramatanga (Organ))
Kurtz DLM, Barry J, Moar D, Olsen K, McGregor R, Vrtar-Huot A, Camille C, Terbasket E, McCrimmon N, Darnay K, Ignace V, Dallaire E, Hicks M, D'Agosto K, Jones C.   +14 more
europepmc   +1 more source

Enhancing Elderly Health Through Physical Activities: Insights From a Global Bibliometric Review, 1900–2023

AGING MEDICINE, EarlyView.
Bibliometric analysis reveals rising global research on physical activity and elderly health, dominated by developed nations. Key hotspots include healthy aging, physical activity's mental health benefits, and VR exercise interventions. Promoting physical activity is vital for healthy aging, requiring greater technology integration and research from ...
Hongman Wang, Bo Xie, Can Liu, Yifan Song   +3 more
wiley   +1 more source

Endoscopic Submucosal Dissection for Colorectal Neoplasms: Is the West Catching Up? [PDF]

Cancers (Basel)
Vohra I, Gopakumar H, Meyyappan A, Chen C, Blatter G, Martins B, Thakkar S, Sharma N.   +7 more
europepmc   +1 more source

Regional Differences in U.S. Consumer Preferences for Native Woody Shrubs With Varying Aesthetic Characteristics

Agribusiness, EarlyView.
ABSTRACT Native plants offer a variety of aesthetic (e.g., fall colour, fruit, flowers) and functional benefits (e.g., pollinator friendly, wildlife friendly, water management). How these benefits influence consumer choice and perceived value of native versus introduced plants is not well understood.
Alicia Rihn, Ariana P. Torres, Sue Barton, Bridget K. Behe   +3 more
wiley   +1 more source