A quality by design (QbD) twin—screw extrusion wet granulation approach for processing water insoluble drugs [PDF]
In this study, a Quality by Design (QbD) approach was used to identify the effect of formulation parameters in a twin screw wet extrusion granulation process for the manufacturing of ibuprofen (IBU) granules with increased dissolution rates. A fractional
Dey, Tumpa +5 more
core +2 more sources
ABSTRACT This study examined whether enzymatic modification of soybean oil (SBO) can be tailored to produce trans‐free fats with physicochemical properties comparable to palm olein, stearin, or palm‐mid fractions (PMFs). US‐grown SBO was modified by lipase‐catalyzed acidolysis using palmitic acid at linearly interpolated substrate molar ratios (C16:0 ...
Ityotagher P. Aondoakaa +2 more
wiley +1 more source
Twin Screw Granulation: Effects of Properties of Primary Powders
Lactose and mannitol are some of the most commonly used powders in the pharmaceutical industry. The limited research published so far highlights the effects of process and formulation parameters on the properties of the granules and the tablets produced ...
Sushma V. Lute +2 more
doaj +1 more source
Scaling of Planar Sodium‐Nickel Chloride Battery Cells to 90 cm2 Active Area
Large planar Na β′′ alumina electrolytes are prepared by tape‐casting and die‐pressing. These ceramic electrolytes are used to prepare planar sodium‐nickel chloride cells with 90 cm2 active area, providing a high capacity of 7 Ah. Successful cell cycling is demonstrated at 300 °C at rates up to C/4 (20 mA cm−2) for a cumulative capacity of 3.6 Ah cm−2.
T. Lan +10 more
wiley +1 more source
Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma +8 more
wiley +1 more source
Date syrup are used as sweetener in bread. Bread with date syrup had superior phenolic composition, better antioxidant properties and carbohydrate hydrolysing enzymes while bread with granulated sugar had higher predicted glyceamic index. The study concluded that date syrup could be the next though‐out ingredient for dual purpose in bread. ABSTRACT The
Akinsola Albert Famuwagun +7 more
wiley +1 more source
Design and evaluation of effervescent floating tablets based on hydroxyethyl cellulose and sodium alginate using pentoxifylline as a model drug [PDF]
The aim of this work was to design and evaluate effervescent floating gastro-retentive drug delivery matrix tablets with sustained-release behavior using a binary mixture of hydroxyethyl cellulose and sodium alginate.
Abdel Rahim, S. +2 more
core +2 more sources
A multifunctional SFMA9/PF1 semi‐interpenetrating hydrogel with excellent conductivity, antioxidant activity, and freeze resistance effectively regulates the wound microenvironment, reduces oxidative stress and inflammation, promotes angiogenesis, and accelerates full‐thickness skin regeneration.
Xiaomin Sun +7 more
wiley +1 more source
3D‐Printed Models in Oral Surgery Simulation Training: A Scoping Review
ABSTRACT Background Advancements in three‐dimensional (3D) printing have introduced innovative tools for medical and dental education. In dental surgery, 3D‐printed simulation models offer valuable presurgical training. This review explores the scope, study types, key findings, limitations, and future research needs to enhance their application in ...
Shahrzad Rahimizadeh Nahavandi +5 more
wiley +1 more source
A novel approach to support formulation design on twin screw wet granulation technology : understanding the impact of overarching excipient properties on drug product quality attributes [PDF]
The overall objective of this work is to understand how excipient characteristics influence the drug product quality attributes and process performance of a continuous twin screw wet granulation process.
De Beer, Thomas +5 more
core +2 more sources

