Results 1 to 10 of about 65,945 (217)

Introduction of whole genome sequencing as NHS standard of care for glioma patients in two neurosurgical oncology centres: West Midlands [PDF]

BJC Reports
Background The challenges of introducing Whole Genome Sequencing (WGS) as NHS standard of care for patients with glioma are reviewed. Methods Patients undergoing glioma surgery with WGS sampling were identified retrospectively from WGS reports between 01/
Victoria Wykes, Erminia Albanese, Vassili Crispi, Sana Manan, Taufiq Khan, Naomi Cole, Christine Bennett, Lowri Hughes, Natasha Vafadar, Vinton Cheng, Ute Pohl, Manoj Raghavan, Yvonne Wallis, Colin Watts   +13 more
doaj   +2 more sources

Improved genomic characterization of a clinically heterogeneous pediatric cohort with WGS vs. WES [PDF]

Scientific Reports
Whole genome sequencing (WGS) comprehensively detects DNA sequence variation, enabling assessment of genetic disorders. The primary aim of this study was to investigate the diagnostic utility of WGS for pediatric musculoskeletal disorders by comparing it
Awtum M. Brashear, Anxhela G. Gustafson, Andrew Quitadamo, Emily Evangelista, Daelyn Quinn, Samuel P. Strom, Holly L. Snyder, Mauro Longoni, Kamran Shazand   +8 more
doaj   +2 more sources

Sanger validation of WGS variants

Scientific Reports
With the development of next-generation sequencing (NGS) technologies it became possible to simultaneously analyze millions of variants. Despite the quality improvement, it is generally still required to confirm the variants before reporting. However, in
Arina Kopernik, Mariia Sayganova, Gaukhar Zobkova, Natalia Doroschuk, Anna Smirnova, Daria Molodtsova-Zolotukhina, Olesya Sagaydak, Oxana Ryzhkova, Sergey Kutsev, Olga Groznova, Lyusya Melikyan, Elizaveta Bondarchuk, Mary Woroncow, Eugene Albert, Viktor Bogdanov, Pavel Volchkov   +15 more
doaj   +3 more sources

Single whole genome sequencing analysis blazes the trail for precision medicine

Cancer Biology & Therapy, 2022
As precision oncology evolves toward developing more targeted therapies, sequencing has moved to the forefront of treatment decision-making. Whole genome sequencing (WGS) has emerged as a technology capable of identifying candidates for rare and targeted
Giulia C. Napoli, Cindy H. Chau, William D. Figg   +2 more
doaj   +1 more source

Exploring transmission dynamics in epidemiologically linked pulmonary tuberculosis cases and household contacts: a WGS-based investigation. [PDF]

BMC Genomics
Seid G, Cabibbe AM, Zerihun B, Alemu A, Diriba G, Tadesse G, Sabiiti W, Moghaddasi K, Iannucci I, Cirillo DM, Abdela S, Mariam SH, Gumi B.   +12 more
europepmc   +2 more sources

Whole Genome Sequencing for Studying Bacillus anthracis from an Outbreak in the Abruzzo Region of Italy

Microorganisms, 2020
Anthrax is a serious infectious disease caused by the gram-positive and spore-forming bacterium Bacillus anthracis. In Italy, anthrax is an endemic disease with sporadic cases each year and few outbreaks, especially in Southern Italy.
Alexandra Chiaverini, Mostafa Y. Abdel-Glil, Jörg Linde, Domenico Galante, Valeria Rondinone, Antonio Fasanella, Cesare Cammà, Nicola D’Alterio, Giuliano Garofolo, Herbert Tomaso   +9 more
doaj   +1 more source

Mink SARS-CoV-2 infection in Poland – short communication

Journal of Veterinary Research, 2021
Since April 2020, when the first SARS-CoV-2 infection was reported in mink and subsequently in mink farm workers in the Netherlands, it has been confirmed that human-to-mink and mink-to-human transmission can occur.
Domańska-Blicharz Katarzyna, Orłowska Anna, Smreczak Marcin, Niemczuk Krzysztof, Iwan Ewelina, Bomba Arkadiusz, Lisowska Anna, Opolska Justyna, Trębas Paweł, Potyrało Patrycja, Kawiak-Sadurska Magdalena, Rola Jerzy   +11 more
doaj   +1 more source

The Molecular Approaches and Challenges of Streptococcus pneumoniae Serotyping for Epidemiological Surveillance in the Vaccine Era

Polish Journal of Microbiology, 2023
Streptococcus pneumoniae (pneumococcus) belongs to the Gram-positive cocci. This bacterium typically colonizes the nasopharyngeal region of healthy individuals.
Abdul Rahman Nurul Asyikin, Mohd Desa Mohd Nasir, Masri Siti Norbaya, Taib Niazlin Mohd, Sulaiman Nurshahira, Hazman Hazmin, John James   +6 more
doaj   +1 more source

WG-Alltag

Göttinger Rechtszeitschrift, 2023
Der Fall wurde im WS 2022/23 in der Fortgeschrittenenübung im Strafrecht an der Georg-August-Universität Göttingen gestellt. Im Kern geht es um die Konstellation des kontaktlosen Bezahlens mit fremder EC-Karte, die noch nicht abschließend geklärt ist. Die Bearbeiter:innen mussten demgemäß mit Delikten, die als gesteigert schwierig empfunden werden, und
Peter Rackow, Emilia Wehlitz
openaire   +1 more source

Heterogeneity in susceptibility to hydroxychloroquine of SARS-CoV-2 isolates

Frontiers in Bioscience-Landmark, 2021
Background: Despite the fact that the clinical efficacy of hydroxychloroquine is still controversial, it has been demonstrated in vitro to control SARS-CoV-2 multiplication on Vero E6 cells.
Celine Boschi, Marion Le Bideau, Julien Andreani, Sarah Aherfi, Priscilla Jardot, Jeremy Delerce, Mathieu Gendrot, Bruno Pradines, Philippe Colson, Anthony Levasseur, Bernard La Scola   +10 more
doaj   +1 more source