Results 1 to 10 of about 162,110 (330)

Targeted and whole-genome sequencing for drug resistance and genetic relatedness inference of rifampicin-resistant Mycobacterium tuberculosis: an in-depth comparison [PDF]

ERJ Open Research
Background Challenges in tuberculosis (TB) control have fuelled interest in routine next generation sequencing (NGS). However, the comparative performance of targeted NGS (tNGS) and whole genome sequencing (WGS) for drug resistance and genetic ...
Miguel de Diego Fuertes, Emilyn Costa Conceição, Felicia Wells, Vincent Rennie, Tim Heupink, Gavin Churchyard, Felix Ndebele, Anneke Van der Spoel Van Dijk, Boitumelo Fanampe, Salome Charalombous, Emmanuel Ayodeji Ogunbayo, Wilma Quispe Rojas, Rob M. Warren, Annelies Van Rie, Anzaan Dippenaar   +14 more
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Sanger validation of WGS variants

Scientific Reports
With the development of next-generation sequencing (NGS) technologies it became possible to simultaneously analyze millions of variants. Despite the quality improvement, it is generally still required to confirm the variants before reporting. However, in
Arina Kopernik, Mariia Sayganova, Gaukhar Zobkova, Natalia Doroschuk, Anna Smirnova, Daria Molodtsova-Zolotukhina, Olesya Sagaydak, Oxana Ryzhkova, Sergey Kutsev, Olga Groznova, Lyusya Melikyan, Elizaveta Bondarchuk, Mary Woroncow, Eugene Albert, Viktor Bogdanov, Pavel Volchkov   +15 more
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Single whole genome sequencing analysis blazes the trail for precision medicine

Cancer Biology & Therapy, 2022
As precision oncology evolves toward developing more targeted therapies, sequencing has moved to the forefront of treatment decision-making. Whole genome sequencing (WGS) has emerged as a technology capable of identifying candidates for rare and targeted
Giulia C. Napoli, Cindy H. Chau, William D. Figg   +2 more
doaj   +1 more source

Whole Genome Sequencing for Studying Bacillus anthracis from an Outbreak in the Abruzzo Region of Italy

Microorganisms, 2020
Anthrax is a serious infectious disease caused by the gram-positive and spore-forming bacterium Bacillus anthracis. In Italy, anthrax is an endemic disease with sporadic cases each year and few outbreaks, especially in Southern Italy.
Alexandra Chiaverini, Mostafa Y. Abdel-Glil, Jörg Linde, Domenico Galante, Valeria Rondinone, Antonio Fasanella, Cesare Cammà, Nicola D’Alterio, Giuliano Garofolo, Herbert Tomaso   +9 more
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Mink SARS-CoV-2 infection in Poland – short communication

Journal of Veterinary Research, 2021
Since April 2020, when the first SARS-CoV-2 infection was reported in mink and subsequently in mink farm workers in the Netherlands, it has been confirmed that human-to-mink and mink-to-human transmission can occur.
Domańska-Blicharz Katarzyna, Orłowska Anna, Smreczak Marcin, Niemczuk Krzysztof, Iwan Ewelina, Bomba Arkadiusz, Lisowska Anna, Opolska Justyna, Trębas Paweł, Potyrało Patrycja, Kawiak-Sadurska Magdalena, Rola Jerzy   +11 more
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The Molecular Approaches and Challenges of Streptococcus pneumoniae Serotyping for Epidemiological Surveillance in the Vaccine Era

Polish Journal of Microbiology, 2023
Streptococcus pneumoniae (pneumococcus) belongs to the Gram-positive cocci. This bacterium typically colonizes the nasopharyngeal region of healthy individuals.
Abdul Rahman Nurul Asyikin, Mohd Desa Mohd Nasir, Masri Siti Norbaya, Taib Niazlin Mohd, Sulaiman Nurshahira, Hazman Hazmin, John James   +6 more
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WG-Alltag

Göttinger Rechtszeitschrift, 2023
Der Fall wurde im WS 2022/23 in der Fortgeschrittenenübung im Strafrecht an der Georg-August-Universität Göttingen gestellt. Im Kern geht es um die Konstellation des kontaktlosen Bezahlens mit fremder EC-Karte, die noch nicht abschließend geklärt ist. Die Bearbeiter:innen mussten demgemäß mit Delikten, die als gesteigert schwierig empfunden werden, und
Peter Rackow, Emilia Wehlitz
openaire   +1 more source

Heterogeneity in susceptibility to hydroxychloroquine of SARS-CoV-2 isolates

Frontiers in Bioscience-Landmark, 2021
Background: Despite the fact that the clinical efficacy of hydroxychloroquine is still controversial, it has been demonstrated in vitro to control SARS-CoV-2 multiplication on Vero E6 cells.
Celine Boschi, Marion Le Bideau, Julien Andreani, Sarah Aherfi, Priscilla Jardot, Jeremy Delerce, Mathieu Gendrot, Bruno Pradines, Philippe Colson, Anthony Levasseur, Bernard La Scola   +10 more
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Attitudes of geneticists and patients toward incidental findings in Saudi Arabia

Journal of Biochemical and Clinical Genetics, 2019
Background: In Middle East countries, including Saudi Arabia, 60%–70% of all marriages occur between first cousins, leading to uniquely common genetic disorders compared to Western countries.
Taghrid Aloraini, Alya Abdulrahim, Gulsan A. Karbani   +2 more
doaj   +1 more source

Emergence of optrA-Mediated Linezolid Resistance in Enterococcus faecium: A Molecular Investigation in a Tertiary Hospital of Southwest China from 2014–2018

Infection and Drug Resistance, 2022
Miao Yi,1 Jiaqi Zou,2 Jinxin Zhao,1 Yu Tang,3 Yaling Yuan,1 Bingxue Yang,1 Jinzhu Huang,1 Peiwen Xia,1 Yun Xia1 1Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China ...
Yi M, Zou J, Zhao J, Tang Y, Yuan Y, Yang B, Huang J, Xia P, Xia Y   +8 more
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