Results 161 to 170 of about 11,128 (261)

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

open access: yesThe FEBS Journal, EarlyView.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior   +5 more
wiley   +1 more source

TRIM32 controls timely cell cycle exit in muscular differentiation through downregulation of c‐Myc mRNA

open access: yesThe FEBS Journal, EarlyView.
Trim32 regulates the transition from proliferation to differentiation in C2C12 cells after myogenic induction. We found that, at the onset of differentiation, Trim32 destabilizes c‐Myc mRNA, promotes cell cycle exit, and enables normal myotube formation.
Lu Xiong   +6 more
wiley   +1 more source

A hedgehog cathelicidin-derived peptide exhibits antiviral activity against herpes simplex virus type 1 infection. [PDF]

open access: yesFront Microbiol
Deng E   +9 more
europepmc   +1 more source

Forest disturbance and the spread of invasive species disrupt diel activity patterns in New Guinea ant communities

open access: yesInsect Conservation and Diversity, EarlyView.
Primary forests hosted more diurnal species and exhibited significant diel specialization. Secondary forests were less species‐rich, dominated by invasive ants, with reduced diel partitioning and more species active at night. Although the overall ant activity was higher during the day, this pattern was stratum‐dependent: arboreal and terrestrial ants ...
Jan Lenc   +4 more
wiley   +1 more source

Collaborative platooning and routing for mixed fleets of electric automated vehicles and conventional trucks

open access: yesInternational Transactions in Operational Research, EarlyView.
Abstract The application of automated ground vehicles (AGVs) is well‐established in closed environments such as port terminals, while their operation in open areas remains challenging. In this work, we set out to overcome this limitation by introducing platooning as a transfer mode in heterogeneous vehicle networks.
Nadia Pourmohammad‐Zia   +2 more
wiley   +1 more source

What do public contributors with lived experience know and think about open research? ‘Nobody should look at results and think “how did they arrive at that?”’

open access: yesJournal of Neuropsychology, EarlyView.
Abstract Involving people with lived experience in research (patient and public involvement or co‐production) is one principle of open research (transparent research practices). Involvement of experts by experience helps ensure that clinical and health research is relevant, ethical and accessible.
Ellen Poliakoff   +7 more
wiley   +1 more source

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