Endocarditis and systemic embolization from Whipple’s disease [PDF]
IDCases, 2021 Whipple’s disease (WD), caused by infection with the organism Tropheryma whipplei, is a rare disease that classically presents with diarrhea, weight loss, and polyarthralgia.
Yu Ting He +4 more
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Could CT abdomen and PET/CT be helpful in early diagnosis of Whipple’s disease? A case report [PDF]
IDCases, 2021 Whipple’s disease is a rare disease, which can be fatal if not treated. It is often diagnosed at a late stage because of the varied disease presentation and its rare incidence.
Renu Kadian +2 more
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Differential diagnostic value of rheumatic symptoms in patients with Whipple’s disease [PDF]
Scientific Reports, 2021 Most patients with Whipple’s disease have rheumatic symptoms. The aim of our prospective, questionnaire-based, non-interventional clinical study was to assess whether these symptoms are useful in guiding the differential diagnosis to the rheumatic ...
Gerhard E. Feurle +6 more
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Tumor Necrosis Factor Inhibitors Exacerbate Whipple’s Disease by Reprogramming Macrophage and Inducing Apoptosis [PDF]
Frontiers in Immunology, 2021 Tropheryma whipplei is the agent of Whipple’s disease, a rare systemic disease characterized by macrophage infiltration of the intestinal mucosa. The disease first manifests as arthralgia and/or arthropathy that usually precede the diagnosis by years ...
Asma Boumaza +11 more
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Whipple’s disease presenting as weight gain and constipation in a Chinese woman [PDF]
BMC Infectious Diseases, 2023 Background Whipple’s disease is a chronic infection due to Tropheryma whipplei, commonly reported in the Caucasian but not in the Chinese population.
Haiyan Ye +8 more
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Delayed Diagnosis of Whipple’s Disease Complicated by Jarisch–Herxheimer Reaction to Ceftriaxone Treatment: A Case Report and Literature Review [PDF]
Tropical Medicine and Infectious Disease, 2022 Whipple’s disease is a rare chronic infection caused by the actinomycete Tropheryma whipplei. Patients commonly present with gastrointestinal symptoms. We present a case of classic Whipple’s disease complicated by a probable Jarisch–Herxheimer reaction ...
Marcus C. C. Clarke, Ric N. Price
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Eyelid abscess as an initial manifestation of whipple’s disease: a case report and comprehensive literature review [PDF]
BMC OphthalmologyBackground Whipple’s disease, caused by Tropheryma whipplei, is a rare chronic infection predominantly affecting the gastrointestinal tract. Ocular involvement is uncommon, and periorbital manifestations are exceedingly rare.
Ashwaq Yahya Asiri +4 more
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Clinical manifestations of Whipple’s disease mimicking rheumatic disorders [PDF]
Rheumatology, 2021 Whipple’s disease is a rare, chronic, systemic disorder caused by Tropheryma whipplei infection. The most common symptoms are weight loss, arthralgia, diarrhea and abdominal pain. Other organ involvement can also occur in the patients.
Eugeniusz J. Kucharz +3 more
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Whipple’s disease: a fatal mimic [PDF]
Autopsy and Case Reports, 2021 Whipple’s Disease, a rare diagnosis caused by the slow-growing bacterium Tropheryma whipplei, most often presents with the classically described signs of malabsorption due to gastrointestinal colonization.
Benjamin Kukull +3 more
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IRF4 haploinsufficiency in a multiplex family with Whipple’s diseaseIRF4 deficiency and Whipple’s disease [PDF]
Journal of Human ImmunityWe report two patients with Whipple’s disease caused by autosomal dominant IRF4 deficiency.
Sinem Ünal +12 more
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