Results 81 to 90 of about 4,957 (152)

Advances in pancreatic cancer early diagnosis, prevention, and treatment: The past, the present, and the future

open access: yesCA: A Cancer Journal for Clinicians, Volume 76, Issue 1, January/February 2026.
Abstract Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a dismal prognosis, largely because of late‐stage diagnosis and therapeutic resistance. PDAC incidence has been rising, with modifiable and non‐modifiable risk factors contributing to disease development.
Alessandro Mannucci, Ajay Goel
wiley   +1 more source

Whipple’s Disease Affecting Ileal Peyer’s Patches: The First Case Report

open access: yesCase Reports in Pathology, 2019
Whipple’s disease is a rare chronic systemic bacterial infectious disease which can affect multiple organs, with a wide clinical spectrum encompassing many symptoms presenting in various forms and combinations.
Sabah Sid’Amar, Giacomo Puppa
doaj   +1 more source

A difficult diagnosis of coeliac disease: Repeat duodenal histology increases diagnostic yield in patients with concomitant causes of villous atrophy [PDF]

open access: yes, 2017
Villous atrophy in absence of coeliac disease (CD)-specific antibodies represents a diagnostic dilemma. We report a case of a woman with anaemia, weight loss and diarrhoea with an initial diagnosis of seronegative CD and a histological documented villous
Cappello, Maria   +5 more
core   +1 more source

Predicting Benefit of Neoadjuvant Chemotherapy and Elective Nodal Irradiation in Pancreatic Adenocarcinoma: A Supervised Machine Learning Approach

open access: yesCancer Medicine, Volume 14, Issue 23, December 2025.
ABSTRACT Background The relative benefit of neoadjuvant therapies remains controversial for patients with (borderline) resectable pancreatic ductal adenocarcinoma (PDAC). The purpose of this study was to create a model to predict response to multiagent neoadjuvant chemotherapy (NAC) followed by radiotherapy with elective nodal irradiation (ENI ...
Garrett K. Harada   +9 more
wiley   +1 more source

Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]

open access: yes, 2020
Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima   +18 more
core  

Whipple's Disease in a 61-Year-Old Patient. Clinical Follow-Up

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to present a clinical observation of a patient with Whipple's disease, demonstrating the difficulties in diagnosing the disease.Key points. A clinical observation of Whipple's disease in a 61-year-old man is described.
Zh. G. Simonova   +4 more
doaj   +1 more source

Radical Pancreaticoduodenectomy for Benign Disease

open access: yesThe Scientific World Journal, 2008
Whipple's procedure is the treatment of choice for pancreatic and periampullary malignancies. Preoperative histological confirmation of malignancy is frequently unavailable and some patients will subsequently be found to have benign disease.
D. O. Kavanagh   +6 more
doaj   +1 more source

Tropheryma whipplei aortic valve endocarditis, cured without surgical treatment

open access: yesBMC Research Notes, 2012
Background Culture-negative endocarditis due to Tropheryma whipplei is a rare disease. Mostly the diagnosis is made by histologic examination of resected heart valve tissue.
Algin Ahmet   +4 more
doaj   +1 more source

Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate [PDF]

open access: yes, 2010
Gastrointestinal involvement in Langerhans cells histiocytosis (LCH) is extremely rare. An optimal treatment regimen is not defined yet and its prognosis is relatively poor.
Agreda Vásquez, Gladys Patricia   +4 more
core  

Mesenteric lymphadenitis as a presenting feature of Whipple’s disease: Value of PCR analysis

open access: yesInternational Journal of Infectious Diseases, 2018
Whipple’s disease (WD) is a rare chronic and systemic infection caused by the ubiquitous actinomycete Tropheryma whipplei. A case of localized infection with mesenteric adenopathy associated with a prolonged unexplained fever is reported herein ...
Lucie Wartique   +4 more
doaj   +1 more source

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