Results 161 to 170 of about 3,094,165 (247)

Interaction between white coat effect and hypertension on arterial stiffness

open access: yes
OBJECTIVE: White coat effect (WCE) is a debated risk factor for cardiovascular diseases (CVD), and the current findings regarding its association with arterial stiffness in hypertension remain inconsistent.
Ma, Jing   +9 more
core   +1 more source

HLA‐A*11:01 Identifies Patients at Risk for Persistent Viraemia and Advanced Fibrosis in HDV Infection

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
The HLA‐A*11:01 allele is associated with persistent viraemia and advanced liver fibrosis in HDV infection. HLA‐A*11:01 carriers exhibit a reduced T‐cell repertoire, suggesting a narrower T‐cell response to the infection. ABSTRACT Background Hepatitis delta virus (HDV) infection causes the most severe form of viral hepatitis, with highly heterogeneous ...
Maria Francesca Cortese   +11 more
wiley   +1 more source

Prospective randomised double‐blind trial: holmium laser lithotripsy with vs without Moses™ 2.0

open access: yesBJU International, EarlyView.
Objective To assess the effect of Moses™ 2.0 (Lumenis Be Ltd., Yokneam Illit, Israel; Boston Scientific, Marlborough, MA, USA) for lithotripsy of renal stones of 8–20 mm in diameter on operative time, surgeon workload, and retropulsion. Subjects/Patients and Methods In our multicentre, randomised, double‐blind clinical trial, patients were randomised 1:
Kimberly A. Maciolek   +19 more
wiley   +1 more source

Cardiovascular Alterations and Management of Patients With White Coat Hypertension: A Meta-Analysis. [PDF]

open access: yesFront Pharmacol, 2020
Xiang H   +6 more
europepmc   +1 more source

Direct evidence implicating the asymmetrical dimethylarginine (ADMA)‐dimethylarginine dimethylaminohydrolase 1 (DDAH1) pathway in cerebrovascular dysfunction and stroke pathogenesis in mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Asymmetrical dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS), whereas dimethylaminohydrolase 1 (DDAH1) is primarily responsible for its metabolism. However, the roles of DDAH1 in cerebrovascular regulation are poorly understood. Furthermore, despite evidence that elevated ADMA levels are
Arun Flynn   +10 more
wiley   +1 more source

Kininase I drives angiotensin II‐induced hypertension through activation of the bradykinin B1 receptor

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Kininase I, comprising carboxypeptidase N (CPN) and carboxypeptidase M, regulates kinin activity and is up‐regulated during injury, inflammation and immune activation. Under these conditions, kininase I converts bradykinin and kallidin into des‐Arg kinins, primary endogenous agonists of the bradykinin B1 receptor (R ...
Acacia White   +5 more
wiley   +1 more source

Hyperlipidaemia in youth with type 1 diabetes: Are current guidelines clinically useful?

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims Dyslipidaemia in youth with type 1 diabetes mellitus (T1D) is emerging as an important modifiable cardiovascular risk factor. International consensus guidelines to screen this entity have evolved over time. To further evaluate this in an Australian context, we investigated adherence to such guidelines over the course of patient care ...
Farrah Rodrigues   +2 more
wiley   +1 more source

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