Results 171 to 180 of about 3,046,663 (238)

Layoffs in automobile manufacturing and mortality among remaining workers. [PDF]

J Epidemiol Community Health
Chen KT, Picciotto S, Bradshaw PT, Ahern J, Eisen EA.   +4 more
europepmc   +1 more source

Population Pharmacokinetics and Exposure‐Response Analyses to Support Cofetuzumab Pelidotin (ABBV‐647) Dose Optimization in Non‐Small Cell Lung Cancer Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Cofetuzumab pelidotin (Cofe‐P) is an anti‐protein tyrosine kinase 7 (PTK7) antibody‐drug conjugate (ADC) being investigated for the treatment of adults with PTK7‐expressing, recurrent non‐small cell lung cancer (NSCLC). The first‐in‐human (FIH) trial demonstrated tolerability of dosages ≤ 2.8 mg/kg once every 3 weeks (Q3W) and ≤ 3.2 mg/kg Q2W ...
Carla Biesdorf, Melanie Rinas, Benjamin Engelhardt, Rabih Saab, Cen Guo, Cristiano Ferlini, Kevin J. Freise, Rajeev M. Menon, Akshanth R. Polepally   +8 more
wiley   +1 more source

Moderating Effects of Muscle Fitness on the Associations Between Work Stress, Burnout, and Well-Being Among White-Collar Workers. [PDF]

Healthcare (Basel)
Huang SL, Wang WH, Li RH, Chen HY, Tang FC.   +4 more
europepmc   +1 more source

Phase I Evaluation of Siltartoxatug, a First‐in‐Class Anti‐Tetanus Monoclonal Antibody: Safety, Pharmacokinetics and Pharmacodynamics in Healthy Australian and Chinese Populations

Clinical Pharmacology &Therapeutics, EarlyView.
Siltartoxatug, a first‐in‐class monoclonal antibody targeting tetanus toxin for post‐exposure prophylaxis, was evaluated in two phase I trials in Australian and Chinese healthy adults. In these randomized, double‐blind, placebo‐controlled, dose‐escalation studies, participants received a single intramuscular injection of siltartoxatug (10–250 μg/kg) or
Xinyu Liu, Zhigang Liu, Xiaohu Kuang, Yueming Wang, Xiaoyi Liu, Jiyuan Ding, Xia Zhou, Xin Zhou, Qianyu Liang, Meizhuo Zhang, Hao Zhao, Qingqing Tan, Weihong Zheng, Huaxin Liao, Charlotte Lemech, Wanmei Wang   +15 more
wiley   +1 more source

Association between psychosocial safety climate and depression risk among Korean workers. [PDF]

Epidemiol Health
Cho SK, Cho SS, Dollard MF, Loh MY, Kang MY.   +4 more
europepmc   +1 more source

Firm‐Level Corporate Social Responsibility and Employees' Affective Outcomes: A Multilevel Approach

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study advances research on corporate social responsibility (CSR) and employees' work attitudes by distinguishing between employee‐level CSR perceptions and firm‐level CSR practices. Prior research has mainly focused on how employees' perceptions of CSR relate to their affective outcomes; this study extends that perspective by jointly ...
Alexander C. Kraaij, Agnieszka Paruzel, Arnoud de Jong   +2 more
wiley   +1 more source

Traumatic Spinal Cord Injury: A Contemporary Review of Classification, Evaluation, and Acute Management. [PDF]

J Clin Med
McDearman JC, Attelah J, Nourbakhsh A.
europepmc   +1 more source

Hours Since Last Drink Is Associated With Multiple Urine Ethyl Glucuronide Cutoffs Among Individuals With Alcohol Use Disorder

Drug Testing and Analysis, EarlyView.
Higher uEtG results indicated more recent drinking, rather than higher levels of alcohol consumption, and the period of detection of uEtG was shorter than previously reported. Even at low cutoffs, uEtG was best conceptualized as a measure of alcohol consumption in the prior 24 h.
Julianne D. Jett, Mohammad Keshtkar, Emma Seidler, Katharine Palmer, Diana Tyutyunnyk, Rachael Beck, Sara C. Parent, Douglas L. Weeks, Naomi Chaytor, Sterling M. McPherson, Michael G. McDonell   +10 more
wiley   +1 more source

The Hungarian adaptation of the work-related Burnout Assessment Tool (BAT). [PDF]

BMC Psychol
Csordás G, Dorner L, Faragó B, Kiss KM, Mester D.   +4 more
europepmc   +1 more source

Investigation on tunnel stability considering pipe‐roof support with transparent soil technology

Deep Underground Science and Engineering, EarlyView.
This study integrates transparent soil technology, 3D reconstruction and numerical simulation to captures the full‐field deformation of shield tunnel instability. Results demonstrate that pipe‐roof support enhances stability via the “soil‐arching barrier effect,” effectively restraining failure wedge development by extending stress transfer paths ...
Zhi Jia, Yunpeng Ji, Zhao Lu, Honghua Zhao, Limin Zhang   +4 more
wiley   +1 more source